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Gastroenterology news
Growing liver tissue directly in the body could ease donor organ shortage
In patients developing end-stage liver disease, the damage has become too severe for the liver's normally extraordinary regenerative capacity to repair or compensate for it. Once this "point of no return" has been reached, ...
18 hours ago
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A black licorice compound slashes gut inflammation and cell death in IBD models and animals
A new study published in Stem Cell Reports demonstrates how a human stem cell-derived model of the intestine can be used to identify potential therapies for inflammatory bowel disease (IBD), highlighting glycyrrhizin as a ...
Apr 16, 2026
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Confirmed precursor to commonest form of esophageal cancer offers opportunities to catch the disease early
Scientists have found the strongest evidence to date that a condition known as Barrett's esophagus is the starting point for all cases of esophageal adenocarcinoma—the most common type of esophageal cancer in the developed ...
Apr 16, 2026
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A hidden army of zombie immune cells may drive fatty liver disease, inflammation and aging
UCLA researchers have identified a rogue population of immune cells that quietly accumulates in aging tissues and in the livers of people with fatty liver disease. Clearing these cells, they found, dramatically reduced inflammation ...
Apr 16, 2026
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Gut microbes reveal a surprising tie to cortisol spikes during acute stress
The gut microbiome influences numerous physiological processes. Researchers at the University of Vienna have now demonstrated for the first time that, in healthy adults, the diversity of gut bacteria and their capacity to ...
Apr 16, 2026
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Liver cancer roadmap links tumor hallmarks to treatment, including targetable mutations
A new review from the Icahn School of Medicine at Mount Sinai and the Hospital Clínic de Barcelona provides one of the clearest roadmaps to date for understanding and treating liver cancer, one of the deadliest cancers worldwide. ...
Apr 16, 2026
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One-third with inflammatory bowel disease have moderate-to-severe disability, review finds
Moderate-to-severe disability affects nearly one-third of patients with inflammatory bowel disease (IBD), according to a review published online in Inflammatory Bowel Diseases.
Apr 16, 2026
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Sleep deprivation disrupts gut microbiota, worsening colorectal cancer outcomes
Sleep deprivation has long been known to weaken the immune system. Now UF Health Cancer Institute researchers have made a startling discovery: The gut microbiota drives changes to the immune system caused by chronic sleep ...
Apr 16, 2026
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Genetic atlas reveals how human liver cells divide their labor
If scientists could shrink themselves to microscopic size and take a journey through the human body—like the submarine crew in the 1966 science fiction classic "Fantastic Voyage"—one of their first stops would no doubt be ...
Apr 15, 2026
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From benign growth to pancreatic cancer: New study shows how the switch gets flipped
As we age, our cells accumulate genetic changes—mutations—some of which open the door to cancer. Scientists call these mutations "oncogenic," meaning "tumor-producing." By our senior years, we each may harbor as many as 100 ...
Apr 15, 2026
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Gut microbiome serves as key driver of bacterial infection outcomes in fatty liver disease
A research team led by the University of California, Irvine's Joe C. Wen School of Population & Public Health has uncovered a critical biological link explaining why individuals with metabolic dysfunction-associated steatotic ...
Apr 15, 2026
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Poor hygiene and food handling practices increase the risk of bacterial outbreaks in Brazilian households
A significant number of Brazilians engage in improper food hygiene and handling practices at home. Examples include washing meat in the kitchen sink and failing to properly wash vegetables. These findings were revealed by ...
Apr 15, 2026
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Why bowel movements start: Newly identified ATP signaling may explain the colon's strongest contractions
Giant migrating contractions (GMCs) are powerful waves of colonic movement that propel intestinal contents toward the anus and are essential for defecation. Yet despite their physiological importance, the mechanisms that ...
Apr 15, 2026
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Modern lifestyles may be affecting how our bodies recycle estrogen
Our industrialized, modern lifestyles may be increasing how much estrogen (the female sex hormone) gets recycled in our bodies, according to a study published in the journal Proceedings of the National Academy of Sciences. ...
GLP-1 medicine improves liver health independent of weight loss, study finds
Researchers at Toronto's Sinai Health have found that semaglutide—the active ingredient in popular weight loss drugs that mimic the gut hormone GLP-1—acts directly on a subset of liver cells to improve organ function and ...
Apr 14, 2026
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Expanding access to palliative care for patients with advanced liver disease
Advanced liver disease (ALD) occurs when significant scarring causes the liver to lose function. Patients with ALD often have serious health challenges but have limited access to palliative care that could improve their quality ...
Apr 13, 2026
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Epigenetic changes at birth are associated with an infant's microbiome and neurodevelopment
The gut microbiome and epigenetics—molecular switches that turn genes on or off—are intertwined, and both contribute to neurodevelopment, finds a study published in Cell Press Blue. The researchers showed that epigenetic ...
Apr 10, 2026
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Negative effects of artificial sweeteners may pass on to next generation, study suggests
Health organizations are starting to raise concerns about the potential long-term impacts of artificial sweeteners, which taste sweet but—unlike sugar—contain no calories, suggesting they could interfere with energy metabolism ...
Apr 10, 2026
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Should people over 75 continue colonoscopies?
The American Cancer Society recommends screening for colorectal cancer in adults beginning at age 45 and continuing through age 75. However, adults over the age of 75 with a history of precancerous polyps—also known as adenomas—are ...
Apr 10, 2026
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Why fatty liver results can mislead: RNA changes often fail to predict proteins
Fatty liver is an increasingly common disease that can progress toward more severe forms, involving inflammation, fibrosis, and, in some cases, cirrhosis and liver cancer. While it is known that a high-fat diet alters gene ...
Apr 9, 2026
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Rethinking the gut microbiome: Health is not about staying the same, say experts
At any moment, your body hosts trillions of microorganisms, on your skin, in your hair, and especially in your gut. Together they form the microbiome. It plays a crucial role in digestion, immunity, and overall health. Yet ...
Apr 9, 2026
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Gut bacteria linked to levels of latent HIV
The composition of gut bacteria appears to be associated with how much latent HIV remains in the blood of people receiving antiretroviral therapy. This is shown in a new study from Karolinska Institutet, published in Gut ...
Apr 9, 2026
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Study finds sex- and race-based disparities in IBS diagnosis rates among US adults
A national survey study led by UCLA Health and Cedars-Sinai Medical Center has found significant disparities in how irritable bowel syndrome (IBS) is diagnosed across sex and racial groups in the U.S., with men and Black ...
Apr 9, 2026
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Some common IBS treatments are linked to a higher risk of death, say study
A large, long-term study led by Cedars-Sinai Health Sciences University investigators suggests that some medications commonly prescribed to treat irritable bowel syndrome (IBS)—including antidepressants—may be associated ...
Apr 8, 2026
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Gut inflammation may rewire the 'second brain,' triggering lasting motility problems
Research by Milena Bogunovic, MD, Ph.D., associate professor of pathology, sheds light on how inflammation in the gastrointestinal (GI) tract, such as that associated with inflammatory bowel disease (IBD), can lead to long-lasting ...
Apr 8, 2026
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