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Gut microbiome serves as a 'second brain' to regulate our bodies, says researcher
The microorganisms in our intestines play an important role in many bodily processes, from digestion to emotions, and are a key factor in our overall health. A number of modern diseases could be traced to disturbances in ...
40 minutes ago
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Gastroenterology
Rapid liver regeneration: New mechanism is triggered by glutamate just minutes after damage occurs
The liver is a vital organ, crucial to digestion, metabolism and the elimination of toxins. It has a unique ability, regeneration, which allows it to replace liver cells damaged by the very toxins that these cells eliminate. ...
1 hour ago
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Exploring the COVID-19 pandemic's impact on colorectal cancer screening and diagnosis
Two recent studies by researchers from Regenstrief Institute and the Indiana University School of Medicine explore the effect of the pandemic on colorectal cancer screening tests and diagnostic colonoscopies in Central Indiana. ...
1 hour ago
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Protein HKDC1: A new potential target for colon cancer therapy
People with inflammatory bowel disease (IBD) also have an increased risk of developing colorectal cancer. However, the exact mechanisms behind this are still largely unknown.
21 hours ago
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Correcting gut microbiota imbalance after stroke can reduce brain inflammation, opening pathway to potential therapies
An imbalance in ligands, which are molecules produced by the body and the gut microbiota, can affect a key receptor protein that plays a role in brain inflammation after stroke, according to researchers at UTHealth Houston, ...
Mar 25, 2025
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FDA approves Tremfya for active Crohn's disease in adults
The U.S. Food and Drug Administration has approved Johnson & Johnson's Tremfya (guselkumab) for adult patients with moderately to severely active Crohn disease.
Mar 25, 2025
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Treatment options for advanced colorectal cancer
Colorectal cancer is one of the most treatable cancers, especially when detected early. For those in advanced stages, significant advancements in therapies are providing renewed hope.
Mar 25, 2025
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Study identifies gut sensor that propels intestines to move
After every meal, the intestines perform an action called peristalsis—moving food through their hollow interiors with coordinated contractions and relaxations of the smooth muscle.
Mar 24, 2025
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Epstein-Barr virus aggravates ulcerative colitis via macrophage pyroptosis: Findings could yield new therapeutic target
A recent study has revealed how Epstein-Barr virus (EBV) intensifies ulcerative colitis (UC), a debilitating inflammatory bowel disease. Researchers discovered that EBV infection triggers macrophage pyroptosis—a form of ...
Mar 24, 2025
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Younger adults at increased risk for colon cancer
Colon cancers have been steadily increasing among people younger than 50, even as cases have declined among seniors.
Mar 24, 2025
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As stomach cancer rates rise in younger people, knowing symptoms and family history is key
Stomach cancer rates in the United States have been steadily decreasing for decades, but recent trends reveal an increase in early-onset stomach cancer in people younger than 50, particularly women. Trends also reveal younger ...
Mar 24, 2025
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Study shows AI can predict premature deaths in people with inflammatory bowel disease
Almost half of people who died with inflammatory bowel disease (IBD) died prematurely, according to a study published in the Canadian Medical Association Journal that used machine learning models to predict death.
Mar 24, 2025
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Warning signs of colorectal cancer in younger adults
Colorectal cancer, the third-most common cancer in the U.S., has been rising among younger people for the past two decades. It is not one type of cancer but two cancers: colon cancer, which starts in the large intestine, ...
Mar 21, 2025
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Analysis of new colorectal cancer immunotherapy shows more treatment options
A team of researchers from Cleveland Clinic Genomic Medicine share insights from an early set of 19,000 patients to receive immune checkpoint inhibitor treatments for colorectal cancer in the U.S.
Mar 20, 2025
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Lost in translation: One in three Australians with IBD experience a disconnect with their doctor
One in three Australians with inflammatory bowel disease (IBD) left their medical consultations with misunderstandings about what was discussed, posing risks to their safety and the management of their condition, according ...
Mar 20, 2025
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Guideline highlights AI's role in colonoscopy, but calls for more research
The American Gastroenterological Association (AGA) released a new clinical guideline making no recommendation—for or against—the use of computer-aided detection systems (CADe) in colonoscopy. A rigorous review of evidence ...
Mar 20, 2025
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Statins linked to reduced liver cancer risk in major cohort study
Harvard Medical School researchers have found that statin use significantly reduces the risk of hepatocellular carcinoma (HCC) and hepatic decompensation among patients with chronic liver disease (CLD). Statins, particularly ...
Pregnancy irreversibly remodels the mouse intestine, study reveals
Researchers at the Francis Crick Institute have found that the small intestine grows in response to pregnancy in mice. This partially irreversible change may help mice support a pregnancy and prepare for a second.
Mar 19, 2025
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Scientists propose new dietary fiber classification for tailored health benefits
Australian food scientists have reclassified dietary fibers—beyond just soluble and insoluble—to better guide nutritional decisions and drive targeted health food products.
Mar 19, 2025
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Do eggs really make you constipated? A gut expert on what the evidence says
You might've heard too many eggs make you constipated. Influencers on Instagram claim it too. The United Kingdom has slang for it—being "egg bound."
Mar 19, 2025
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The gut in the lab may reveal what gut microbes do in real time
What we eat affects our gut microbes, and now researchers can follow both good and bad changes step by step.
Mar 19, 2025
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Dialysis drug shows promise for combating antibiotic resistance in the gut
Increased antibiotic use can lead, seemingly paradoxically, to more problematic infections, as the bacteria evolve to resist the treatment. The answer to this antimicrobial resistance, which the Centers for Disease Control ...
Mar 18, 2025
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Rethinking functional dyspepsia and gastroparesis: Evidence for disease spectrum challenges traditional classification
Functional dyspepsia (FD) and gastroparesis (GP) are gastrointestinal disorders often managed as separate conditions. FD is classified as a disorder of gut-brain interaction (DGBI), characterized by symptoms such as early ...
Mar 18, 2025
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Exploring Helicobacter pylori treatment practices in the Asia-Pacific region
Helicobacter pylori bacteria is considered to be the main cause of gastric cancer, with the infection rate particularly high in the Asia-Pacific region. Approximately 90% of cases are linked to H. pylori bacterial infections, ...
Mar 18, 2025
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Clinical trial shows promising results for boosting colorectal cancer screening in rural areas
New research shows that a combined effort of mailing stool-based tests and providing patient navigation to follow-up procedures significantly increased screenings for colorectal cancer (CRC) among Medicaid enrollees in rural ...
Mar 17, 2025
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