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Gastroenterology news

Medications

GLP-1 weight-loss meds could interfere with endoscopy, colonoscopy

Food left in the stomach or stool left in the bowel can impede a doctor's ability to successfully perform an endoscopy or colonoscopy.

Health

Q&A: Why your flu shot might come with a colon cancer test

Colorectal cancer cases are rising among younger people, striking even folks without obvious risk factors.

Inflammatory disorders

Study highlights pervasiveness of inflammation in American diet

Almost 6 in 10 Americans have pro-inflammatory diets, increasing the risk of health problems including heart disease and cancer, according to a new study that used a tool designed to examine inflammation in the diet.

Diseases, Conditions, Syndromes

Creating a more accurate model of inflammatory bowel disease

A research team led by Junior Associate Professor Kazuo Takayama, from the Department of Cell Growth and Differentiation, recently constructed a new model of inflammatory bowel disease using iPS cells that enables more accurate ...

Inflammatory disorders

Thaumatin, a natural sweetener with anti-inflammatory potential

A new study by the Leibniz Institute for Food Systems Biology at the Technical University of Munich shows for the first time that bitter tasting protein fragments (peptides) are produced in the stomach during the digestion ...

Diseases, Conditions, Syndromes

How alcohol-associated liver disease differs among races

Researchers have long known that outcomes for alcohol-associated liver disease (ALD) aren't equal among all races and ethnicities in the U.S., but differences among these groups have been less clear.

Neuroscience

Study reveals link between microbiome and aggression in mice

A new study led by Prof. Omry Koren and graduate student Atara Uzan-Yuzari from the Azrieli Faculty of Medicine at Bar-Ilan University has unveiled significant evidence connecting the gut microbiome to aggressive behavior ...

Medical research

It takes cellular teamwork to heal the intestine

Researchers at Baylor College of Medicine have uncovered a more detailed picture of how the intestinal epithelium—the lining of the intestines—heals itself after infection with rotavirus. A meticulous single-cell analytical ...

Diseases, Conditions, Syndromes

AGA recommends change in testing protocol for cirrhosis patients

Patients with cirrhosis, or permanent liver damage, are at higher risk for coagulation disorders, which impact your body's ability to control blood clotting. This puts cirrhosis patients at increased risk of morbidity and ...

Oncology & Cancer

Stomach cancer atlas maps path to better treatments

Scientists in Singapore have assembled the world's largest and highest-resolution atlas of gastric cancer, a leading cause of global cancer death. The atlas provides, at the level of single cells, new insights into how gastric ...

Oncology & Cancer

How chronic intestinal inflammation can cause cancer

Chronic inflammatory bowel disease (IBD) are inflammations of the gastrointestinal tract which flare up in phases and are accompanied by bloody bowel movements, diarrhea and severe impairment of the quality of life. IBD patients ...

Oncology & Cancer

Uncovering how injury to the pancreas impacts cancer formation

Research from scientists at the Vanderbilt University School of Medicine Basic Sciences and the Salk Institute for Biological Studies shows that acinar cells in the pancreas form new cell types to mitigate injury but are ...

Diseases, Conditions, Syndromes

Clinically active IBD linked to adverse COVID-19 outcomes

(HealthDay)—Clinically active inflammatory bowel disease (IBD) is associated with adverse COVID-19 outcomes, especially in younger and middle-aged adults, according to a study published online Sept. 27 in the Journal of ...

Radiology & Imaging

Intestinal ultrasound informs management of IBD

(HealthDay)—Point-of-care (POC) intestinal ultrasound (IUS) affects clinical decision-making in inflammatory bowel disease (IBD) and could reduce the need for endoscopy or magnetic resonance imaging (MRI), according to ...

Oncology & Cancer

Study links gut microbiome and aggressive prostate cancer

Cleveland Clinic researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help reduce risk. Findings from the ...

Immunology

Systemic lupus erythematosus linked to altered gut microbiome

Systemic lupus erythematosis (SLE) is an autoimmune disease in which the immune system targets tissues of the body, causing widespread inflammation and affecting multiple organs such as the kidney and the brain. The gut "microbiome"—all ...

Gerontology & Geriatrics

Polyphenol-rich diets improve leaky gut syndrome in the elderly

The increase of intestinal permeability is associated with factors such as aging, food allergies and intolerances and unhealthy diets. This alteration causes a reduction of the gut integrity barrier that triggers the transit ...

Pediatrics

Gut microbes may help explain benefits of breastfeeding

It has long been known that certain gut bacteria—bifidobacteria—are prevalent in the gut of breastfed infants. Although these bifidobacteria are considered beneficial, the reason why has so far been unclear.

Gastroenterology

Glial cells crucial to maintaining healthy gut immunity

Researchers at the Francis Crick Institute have uncovered a fundamental role of glial cells in the nervous system of the gut in maintaining a healthy intestine. These cells have been found to coordinate the immune responses ...

Immunology

Immunodeficiency affects intestinal microbiome

In the largest study of intestinal bacterial composition (also called the intestinal microbiome) to date in persons with the immunodeficiency selective IgA deficiency, researchers at DTU Bioengineering have ascertained that ...

Diseases, Conditions, Syndromes

New study characterizes the gut virome

A new study has added numerous previously uncharacterized viral genomes and genes to the ever-increasing worldwide pool of human gut viromes. The study, published in mSystems, an open-access journal of the American Society ...

Medications

Tackling the collateral damage from antibiotics

Antibiotics cure bacterial infections and save millions of lives each year. But they can also harm the helpful microbes residing in the gut, weakening one of the body's first lines of defense against pathogens and compromising ...

Immunology

How the immune system keeps the intestinal flora in balance

The bacteria living in the intestine consist of some 500 to 1000 different species. They make up what is known as the intestinal flora, which plays a key role in digestion and prevents infections. Unlike pathogens that invade ...

Gastroenterology

How probiotic bacteria benefit the intestine

Interaction between the gut microbiota and the immune system is important for host physiology and susceptibility to disease, but also for the efficacy of e.g., cancer immunotherapies. A multidisciplinary research team have ...