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Gastroenterology news

Gastroenterology

AI may help predict risk of Barrett's esophagus and esophageal cancer

Precancerous changes in the cells of the esophagus, a condition called Barrett's esophagus, is a risk factor for esophageal cancer. Barrett's esophagus is caused by gastroesophageal reflux disease (GERD), which occurs when ...

Medical research

Tuft cells act as regenerative stem cells in the human intestine, study finds

Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation damage, and contribute ...

Inflammatory disorders

Study highlights pervasiveness of inflammation in American diet

Almost 6 in 10 Americans have pro-inflammatory diets, increasing the risk of health problems including heart disease and cancer, according to a new study that used a tool designed to examine inflammation in the diet.

Diseases, Conditions, Syndromes

Creating a more accurate model of inflammatory bowel disease

A research team led by Junior Associate Professor Kazuo Takayama, from the Department of Cell Growth and Differentiation, recently constructed a new model of inflammatory bowel disease using iPS cells that enables more accurate ...

Inflammatory disorders

Thaumatin, a natural sweetener with anti-inflammatory potential

A new study by the Leibniz Institute for Food Systems Biology at the Technical University of Munich shows for the first time that bitter tasting protein fragments (peptides) are produced in the stomach during the digestion ...

Diseases, Conditions, Syndromes

How alcohol-associated liver disease differs among races

Researchers have long known that outcomes for alcohol-associated liver disease (ALD) aren't equal among all races and ethnicities in the U.S., but differences among these groups have been less clear.

Neuroscience

Study reveals link between microbiome and aggression in mice

A new study led by Prof. Omry Koren and graduate student Atara Uzan-Yuzari from the Azrieli Faculty of Medicine at Bar-Ilan University has unveiled significant evidence connecting the gut microbiome to aggressive behavior ...

Psychology & Psychiatry

Depression linked to bowel conditions

A new study has found depression is more common among people with Crohn's disease or ulcerative colitis in the years before they are diagnosed.

Immunology

Why protecting the brain against infection takes guts

The brain is uniquely protected against invading bacteria and viruses, but its defence mechanism has long remained a mystery. Now, a study in mice, confirmed in human samples, has shown that the brain has a surprising ally ...

Gastroenterology

High-sugar diet can damage the gut, intensifying risk for colitis

Mice fed diets high in sugar developed worse colitis, a type of inflammatory bowel disease (IBD), and researchers examining their large intestines found more of the bacteria that can damage the gut's protective mucus layer.

Medical research

Discoveries reshape understanding of gut microbiome

The human gut is home to microorganisms that outnumber our cells by a factor of 10 to 1. Now, discoveries by scientists at the Oklahoma Medical Research Foundation have redefined how the so-called gut microbiome operates ...

Immunology

Is there a connection between asthma and acid reflux?

Asthma and acid reflux often occur together. It isn't clear why, or whether one causes the other. But we do know that acid reflux can worsen asthma and asthma can worsen acid reflux - especially severe acid reflux, a condition ...

Gastroenterology

Healthy bacteria thrive in the gut before birth

Australian researchers have discovered the gut microbiome—a complex ecosystem of microorganisms made up of bacteria, viruses, fungi and other life forms—is selected and starts developing as early as five months in utero.

Parkinson's & Movement disorders

Gut bacteria could be responsible for side effect of Parkinson's drug

Bacteria in the small intestine can deaminate levodopa, the main drug that is used to treat Parkinson's disease. Bacterial processing of the unabsorbed fractions of the drug results in a metabolite that reduces gut motility. ...

Medical research

Creating an alternative to animal experiments

The human intestine is vital for both digestion and absorbing nutrients as well as drugs. For any type of research that involves intestines, scientists require research models that reflect the physiological situation inside ...