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Gastroenterology news

Diseases, Conditions, Syndromes

How doxycycline for STI prevention affects the gut microbiome

Taking a dose of the oral antibiotic doxycycline after a high-risk sexual encounter has dramatically reduced the incidence of sexually transmitted infections (STIs) in places where the strategy is being tried.

Medical research

Tuft cells act as regenerative stem cells in the human intestine, study finds

Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation damage, and contribute ...

Inflammatory disorders

Study highlights pervasiveness of inflammation in American diet

Almost 6 in 10 Americans have pro-inflammatory diets, increasing the risk of health problems including heart disease and cancer, according to a new study that used a tool designed to examine inflammation in the diet.

Diseases, Conditions, Syndromes

Creating a more accurate model of inflammatory bowel disease

A research team led by Junior Associate Professor Kazuo Takayama, from the Department of Cell Growth and Differentiation, recently constructed a new model of inflammatory bowel disease using iPS cells that enables more accurate ...

Inflammatory disorders

Thaumatin, a natural sweetener with anti-inflammatory potential

A new study by the Leibniz Institute for Food Systems Biology at the Technical University of Munich shows for the first time that bitter tasting protein fragments (peptides) are produced in the stomach during the digestion ...

Diseases, Conditions, Syndromes

How alcohol-associated liver disease differs among races

Researchers have long known that outcomes for alcohol-associated liver disease (ALD) aren't equal among all races and ethnicities in the U.S., but differences among these groups have been less clear.

Neuroscience

Study reveals link between microbiome and aggression in mice

A new study led by Prof. Omry Koren and graduate student Atara Uzan-Yuzari from the Azrieli Faculty of Medicine at Bar-Ilan University has unveiled significant evidence connecting the gut microbiome to aggressive behavior ...

Diabetes

Viruses from poo can help combat obesity and diabetes

Obese mice with unhealthy lifestyles gain significantly less weight and avoid type 2 diabetes when they receive viruses transplanted from the stool of lean mice. These are the findings of a new University of Copenhagen study.

Diseases, Conditions, Syndromes

Guidelines issued for managing eosinophilic esophagitis

(HealthDay)—Recommendations are presented for the management of eosinophilic esophagitis (EoE) in clinical practice guidelines published in the May issue of Gastroenterology.

Gastroenterology

Changes to gut microbiome may slow cancer growth in smokers

Changes to the gut microbiome interacted with the immune system to slow the growth of cancer in mice exposed to cigarette smoke, according to research that was selected for presentation at Digestive Disease Week (DDW) 2020. ...

Medical research

Gut microbes influence how rat brains react to opioids

When Sierra Simpson was in college, she was sick for a year with recurring fevers and vomiting. Her doctors couldn't figure out what she had. Suspecting a bacterial infection, they tried treating her with high doses of antibiotics.

Medical research

New model of the GI tract could speed drug development

MIT engineers have devised a way to speed up the development of new drugs by rapidly testing how well they are absorbed in the small intestine. This approach could also be used to find new ways to improve the absorption of ...

Diseases, Conditions, Syndromes

New findings on hepatitis C in infants can lead to improved treatments

Only about 5% of babies born to mothers with hepatitis C are themselves infected by the disease. A possible reason for this low figure is that the baby's immune system has already destroyed the virus before birth. Researchers ...

Immunology

Transporter's role in gut barrier linked to intestinal dysfunction

The cotransporter NKCC1 moves sodium, potassium and chloride ions across the cell membrane of many cell types, including intestinal epithelial cells. Two patients with mutations in NKCC1 suffered from severe intestinal dysfunction ...

Medical research

Crohn's disease: Preserving inflammation-free phases

Crohn's disease is a chronic inflammatory disorder of the intestine that, in most cases, relapses episodically. As of now, there is no cure for this disease. A research group led by the Technical University of Munich (TUM) ...

Gastroenterology

Suppressing stomach acid may up intestinal growth of MDROs

(HealthDay)—Stomach acid suppression medications increase the odds of intestinal colonization with multidrug-resistant microorganisms (MDROs), according to a review and meta-analysis recently published in JAMA Internal ...

Medical research

Celiac disease linked to increased risk of premature death

People with celiac disease have increased risk of dying prematurely, despite increased awareness of the disease in recent years and better access to gluten-free food. This is according to a new study from Karolinska Institutet ...

Gerontology & Geriatrics

Bacteremia risk higher in older patients hospitalized with IBD

(HealthDay)—Older age is associated with an increased risk for bacteremia in hospitalized patients with inflammatory bowel disease (IBD), according to a study published in the March issue of the United European Gastroenterology ...

Diseases, Conditions, Syndromes

Researchers discuss findings of study on alcohol-related liver disease

Through a unique database, KI researchers have been able to study the risk of mortality among people with liver disease caused by too much alcohol. Principal investigator Hannes Hagström, associate professor at the Department ...

Gastroenterology

Endoscopy within six hours does not lower mortality in GI bleed

(HealthDay)—Endoscopy within six hours versus six to 24 hours after consultation is not associated with lower 30-day mortality in patients with acute upper gastrointestinal bleeding who are at high risk for further bleeding ...