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Genetics news
Genetics
Inducing a gene that informs cell signaling could halt diabetic kidney disease, study shows
New research by Stony Brook Medicine nephrology specialists that centers on targeting key cellular signaling between two types of kidney cells, and inducing a certain gene within those processes, may help prevent or reduce ...
4 minutes ago
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Genetics
An integral T cell pathway has implications for understanding sex-based immune response
The well-established existence of sex differences in immune responses, including immune responses driven by T cells, cuts both ways. Females tend to have a stronger immune response to pathogens, yet most patients who have ...
58 minutes ago
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Stem cell discovery highlights importance of DNA methylation in cancer
A study led by Umeå University, Sweden, presents new insights into how stem cells develop and transition into specialized cells. The discovery can provide increased understanding of how cells divide and grow uncontrollably ...
6 minutes ago
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Novel gene therapy shows promise in targeting a mutation linked to epilepsy
Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) are working on a therapy that holds potential in treating patients with epilepsy, a neurological disorder defined by recurring ...
21 hours ago
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Study uncovers mutations and DNA structures driving bladder cancer
How bladder cancer originates and progresses has been illuminated as never before in a study led by researchers at Weill Cornell Medicine and the New York Genome Center. The researchers found that antiviral enzymes that mutate ...
22 hours ago
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Study: DOCK8 mutation disrupts helper T cell differentiation via glycolytic pathway regulation
A study, published in the journal MedComm and led by Dr. Panpan Jiang and collaborators at Tongji Medical College, explores the critical role of the dedicator of cytokinesis 8 (DOCK8) gene in the differentiation of helper ...
19 hours ago
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Scientists create first map of DNA modification in the developing human brain
A UCLA-led study has provided an unprecedented look at how gene regulation evolves during human brain development, showing how the 3D structure of chromatin—DNA and proteins—plays a critical role. This work offers new ...
Oct 9, 2024
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Newly discovered genetic marker could pave the way for future Alzheimer's disease therapeutics
Indiana University School of Medicine researchers have identified a new genetic marker that could play a role in the development of Alzheimer's disease, which is characterized by two primary pathologies: amyloid-beta plaques ...
Oct 9, 2024
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Study finds new genetic loci associated with dementia
A research team comprising several researchers within the University of Kentucky's Sanders-Brown Center on Aging has investigated the genetic risk of neuropathological traits commonly seen by neuropathologists performing ...
Oct 9, 2024
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The secret to slimming? Special 'skinny genes' double weight loss
The secret to losing weight could all be down to a combination of 14 "skinny genes," a new study has found.
Oct 9, 2024
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Genetic analysis of 25,000 Chinese mothers and infants reveals unique genes associated with disease risk
Genome-wide association studies have great potential for advancing our understanding of the genetic background of diseases, but so far, few association studies have focused on maternal and newborn diseases, and most have ...
Oct 9, 2024
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DAPK3 emerges as a new regulator of migration of triple-negative breast cancer cells
Triple-negative breast cancer (TNBC) is the subtype of breast cancer that is the hardest to treat. TNBC patients account for more than 20,000 cases of this condition annually in the U.S. alone. They experience worse outcomes ...
Oct 8, 2024
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New technique that makes competition between tumor cells visible can help personalize treatments for multiple myeloma
Not all cells within the same cancer are the same. They all have genetic errors that turn them into tumor cells, but these errors are not identical. In each cancer, there are populations of cells with different mutations, ...
Oct 8, 2024
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How diabetes risk genes make cells less resilient to stress
The cells in your pancreas, like people, can only handle so much stress before they start to break down. Certain stressors, such as inflammation and high blood sugar, contribute to the development of type 2 diabetes by overwhelming ...
Oct 8, 2024
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Cell line models identify cause of melanoma with drug resistance
Melanoma is a type of cancer that originates from melanocytes, the cells responsible for producing skin pigment, and is known as the most lethal form of skin cancer due to its high rates of metastasis and recurrence. With ...
Oct 8, 2024
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Nobel scientist uncovered tiny genetic switches with big potential
Harvard geneticist Gary Ruvkun vividly remembers the late-night phone call with his longtime friend and now 2024 Nobel Prize in Medicine co-laureate Victor Ambros, when they made their groundbreaking discovery of genetic ...
Oct 8, 2024
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How epigenetic modifications can influence the onset and progression of various diseases
Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the environment. A review article titled ...
Oct 8, 2024
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U.S. duo wins Nobel Prize in medicine for discovery of microRNA and gene regulation breakthrough
US scientists Victor Ambros and Gary Ruvkun won the Nobel Prize in Medicine on Monday for their discovery of microRNA and its role in how genes are regulated, solving a decades-old mystery, the Nobel Assembly at Sweden's ...
Oct 7, 2024
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Discovery of key gene offers new hope in treating chronic myeloid leukemia
A key gene that could enhance the treatment success rates of chronic myeloid leukemia (CML) has been discovered by researchers.
Oct 7, 2024
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Study finds common breast cancer treatments may speed aging process
A new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center has revealed that common breast cancer treatments, including chemotherapy, radiation, and surgery, may accelerate the biological aging ...
Oct 7, 2024
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Scrutinizing cells for clues to a treatment for muscular dystrophy
A research team led by Associate Professor Hidetoshi Sakurai and Researcher Nana Takenaka-Ninagawa recently demonstrated the superior therapeutic potential of iPS cell-derived mesenchymal stromal cells (iMSCs) compared to ...
Oct 7, 2024
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Study reveals key mechanism driving atherosclerosis in Hutchinson-Gilford progeria syndrome
A team of researchers has made a significant breakthrough in understanding the underlying causes of cardiovascular disease in patients with Hutchinson-Gilford progeria syndrome (HGPS), an ultra-rare genetic disorder that ...
Oct 7, 2024
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A histone post-translational modification linked to lifelong susceptibility to stress in mice
Chemical changes to histones, the proteins that help to pack and organize DNA inside cells, play a key role in determining what genes will be consistently activated over the course of an animal or human's life. Past studies ...
PFAS exposure linked to sleep disruptions in young adults
Research led by the Keck School of Medicine of USC has shown that levels of "forever chemicals" in the blood are linked with disruptions to a fundamental pillar of health—sleep.
Oct 4, 2024
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Research points to potential new treatment for aggressive prostate cancer subtype
When researchers at the University of Michigan Rogel Cancer Center first identified a new subtype of aggressive prostate cancer, they knew they needed to understand how this genetic alteration was driving cancer and how to ...
Oct 4, 2024
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