Researchers have identified a new mutation in the ARPP21 gene that could be the cause of amyotrophic lateral sclerosis (ALS), a devastating neurodegenerative disease. The researchers are from the Neuromuscular Diseases Group ...
Jul 12, 2024
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Obesity is a complicated condition, caused by a combination of genetics, the food environment, behavior, and other factors. For millennia, getting enough food to survive and thrive was difficult. For most people, it's now ...
Jul 15, 2024
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The evolution of resistance to diseases, from infectious illnesses to cancers, poses a formidable challenge.
Jul 15, 2024
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A team of researchers led by Oscar Sánchez-Carranza in Professor Gary Lewin's lab at the Max Delbrück Center have identified a new function for the PIEZO2 protein—in mediating chronic pain hypersensitivity. The research ...
Jul 11, 2024
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Mutations in the KRAS gene are the primary driver of pancreatic cancer. A new class of drugs known as KRAS inhibitors is showing initial promise in clinical trials, but many tumors quickly develop resistance to the treatment.
Jul 11, 2024
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Today, the American Journal of Human Genetics published a perspective piece on the need for an equitable and inclusive future for DNA and ancient DNA (aDNA) research in Africa. The paper, coauthored by an international team ...
Jul 11, 2024
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Those living in disadvantaged neighborhoods have significantly higher activity of stress-related genes, new research suggests, which could contribute to higher rates of aggressive prostate cancer in African American men. ...
Jul 12, 2024
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Cardiovascular disease often culminates in heart failure, a hallmark of which is fibrosis, a form of tissue scarring. Cardiac fibrosis initially repairs damaged heart tissue, but it can quickly become excessive and pathological. ...
Jul 10, 2024
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Researchers from TGen, part of City of Hope, and from the University of California, San Diego have identified a set of genes that helps predict whether a patient's glioblastoma might respond to some promising drugs called ...
Jul 10, 2024
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Posterior fossa group A (PFA) ependymoma are rare, treatment-resistant pediatric tumors of the central nervous system that originate in the brain and spinal cord. They have the highest recurrence rate and poorest prognosis ...
Jul 10, 2024
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