Journal of Experimental Medicine

Alzheimer's disease & dementia

Boosting the brain's waste disposal system

Universitätsmedizin Berlin have been investigating the extent to which macrophages, a type of phagocytic immune cell, might be used to eliminate the abnormal protein deposits typically found in the brains of patients with ...

Medical research

Malaria's key to the liver uncovered

Scientists uncover a port of liver entry for malaria parasites in a report published in The Journal of Experimental Medicine. If these results hold up in humans, drugs that target this entry protein might help prevent the ...

Medical research

Researchers home in on what's wearing out T cells

Sometimes even cells get tired. When the T cells of your immune system are forced to deal over time with cancer or a chronic infection such as HIV or hepatitis C, they can develop 'T cell exhaustion,' becoming less effective ...

Immunology

Immune cell journey has bloody consequences

Immune cells that creep across blood vessels trigger potentially fatal bleeding in platelet-deficient mice, according to a report published in The Journal of Experimental Medicine. If the same is true in humans, blocking ...

Medical research

Stopping malaria in its tracks

A new drug acts as a roadblock for malaria, curing mice of established infection, according to a study in The Journal of Experimental Medicine. Treatment was not associated with obvious side effects, suggesting that the drug ...

Immunology

Drug target for asthma discovered

The over-active immune cells responsible for asthma depend on the gene BCL11B to develop into mature cells, according to a study published in the Journal of Experimental Medicine. The identification of this gene's role could ...

Immunology

New protein found in immune cells

Researchers of the University of Freiburg have discovered Kidins220/ARMS in B cells. They also determined that it plays a decisive role in the production of antibodies and the formation of B cells, which are a type of white ...

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