Scientists identify the genetic 'switches' of bone growth
Scientists at the UNIGE have identified the genetic sequences that regulate the activity of the genes responsible for bone growth.
Jun 14, 2024
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Cells: News and Research on Chromatin
MeSH tree: A11.284.430.106.279.345.190.160.180
Researchers reveal secrets of aging beta cells and their ability to secrete insulin
A new study reveals that aging human pancreatic beta cells display features of senescence while maintaining elevated levels of genes crucial for their function. Despite their aging status, these cells therefore exhibit an ...
Jun 4, 2024
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RNA that doesn't age: Neuroscientists discover building blocks in nerve cells that last a life time
Certain RNA molecules in the nerve cells in the brain last a life time without being renewed. Neuroscientists from Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have now demonstrated that this is the case together ...
Apr 8, 2024
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The architectural role of p53: Early 3D chromatin remodeling to trigger cellular stress response
The simplest explanation of cancer is that, for any reason, a cell in our body ignores its biological program and gets loose, multiplying itself again and again, creating a tumor. This has a lot to do with the wrong use of ...
Apr 5, 2024
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Study reveals the role of the protein Kdm1a in maintaining neuronal identity
Epigenetic processes allow different cell types to emerge from a single genome. Throughout development, cells differentiate and acquire distinct characteristics by expressing the same genome in different ways.
Mar 12, 2024
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Protein integral to sperm development and male fertility identified
Early in the development of sperm, a strange event happens: the X and Y chromosomes condense into tight packages and are sequestered away from the other 44 human chromosomes. If any part of this process goes awry, the cells ...
Feb 22, 2024
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The roles of genes and 3D genome folds in determining health
Whether we stay healthy or become seriously ill is determined by our genes. But also, the folding of our genome has a significant influence on this, as the 3D genome organization regulates which genes are switched on and ...
Jan 30, 2024
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Enabling early detection of cancer with AI-based chromatin biomarkers
The ability to detect a developing tumor at a very early stage and to closely monitor the success or failure of cancer therapy is crucial for a patient's survival. A breakthrough on both counts has now been achieved by researchers ...
Dec 14, 2023
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235
Study shows how genes in retina are regulated during development
Researchers at the National Institutes of Health have mapped the 3D organization of genetic material of key developmental stages of human retinal formation, using intricate models of a retina grown in the lab.
Dec 13, 2023
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Robust chromatin map explains heterogeneity of pediatric acute lymphoblastic leukemia
Scientists at St. Jude Children's Research Hospital described the gene regulatory networks contributing to differences between subtypes of the most common childhood cancer, acute lymphoblastic leukemia (ALL). The work examined ...
Nov 20, 2023
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