MeSH tree: D08.811.913.696.620.682
Diabetic cardiomyopathy (DCM) is a progressive complication associated with type 2 diabetes (T2D), causing deterioration of cardiac function in diabetic patients, independent of coronary artery disease, and hypertension. ...
Sep 28, 2022
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LSU researchers have built a cancer drug discovery engine powered by AI that soon could match any type of cancer, based on a small cell sample from a patient, with the drug most likely to cure that cancer.
Sep 28, 2022
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The liver is the all-important organ behind processing of various substances we put into our bodies, from food and drink to alcohol and drugs. When things go awry with the liver, the consequences can be deadly. At the root ...
Sep 26, 2022
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Long-term memories rely on both the repetition of events and an intricate neurological learning process in making these memories last, shows a new study by a team of neuroscientists. Its findings provide a more detailed understanding ...
Sep 26, 2022
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The advent of small-molecule targeted therapies, a decade ago, revolutionized the treatment of metastatic melanoma, provided that the tumors carry the mutations to respond to these treatments. However, despite a remarkable ...
Sep 22, 2022
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Huntington's disease (HD) is a hereditary brain disease caused by a mutation in the huntingtin gene. HD is a neurodegenerative disease without a cure that, after the onset of the disease at around 40 years of age, causes ...
Sep 19, 2022
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The multitargeted tyrosine kinase inhibitor (MKI), lenvatinib, is widely used to treat advanced and metastatic thyroid cancer. However, the molecular mechanisms by which thyroid cancer cells become resistant to lenvatinib ...
Sep 13, 2022
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Researchers from The University of Texas MD Anderson Cancer Center reported study results showing that the targeted therapy fruquintinib significantly improved overall survival (OS) and progression-free survival (PFS) in ...
Sep 12, 2022
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Constitutively activated G proteins caused by specific mutations mediate the development of multiple malignancies. The mutated Gαq/11 are perceived as oncogenic drivers in the vast majority of uveal melanoma (UM) cases, making ...
Sep 5, 2022
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Checkpoint inhibitor drugs have been a gamechanger for many cancer patients. Yet about 70% don't respond to these medications, which work by removing the "brakes" on the immune system's response to a tumor.
Aug 1, 2022
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