MeSH tree: D08.811.277.656.918
One fundamental feature of neurodegenerative diseases is a breakdown in communication. Even before brain cells die, the delicate machinery that keeps neurons in touch—by clearing away protein waste at the synapses—starts ...
Sep 15, 2025
0
80
Human eggs are some of the most patient cells in the body, lying dormant for decades until needed. A study published in The EMBO Journal shows that the cells deliberately slow the activity of their internal waste disposal ...
Jul 16, 2025
0
10
A disrupted protein degradation process in heart muscle cells can lead to a range of severe heart diseases. In the case of dilated cardiomyopathy, a pathological enlargement of the heart chambers, researchers at the Max Planck ...
Feb 4, 2025
0
35
Aging is an inevitable phenomenon and is accompanied by several comorbidities. To this end, research into the effects of aging has become paramount, and scientists are looking for ways to slow down aging and its detrimental ...
Sep 25, 2024
0
2
Proteins are the workhorses of life. Organisms use them as building blocks, receptors, processors, couriers and catalysts. A protein's structure is critical to its function. Malformed proteins not only fail to carry out their ...
Apr 30, 2024
0
66
The typical job of the proteasome, the garbage disposal of the cell, is to grind down proteins into smaller bits and recycle some of those bits and parts. That's still the case, for the most part, but, Johns Hopkins Medicine ...
Apr 12, 2024
0
67
Virginia Tech researchers have discovered a new function for a common protein in the brain—a development that sheds new light on the mysteries of the mind and holds promising implications for the treatment of memory loss ...
Jan 25, 2024
0
10
Smart users of social media protect themselves by deleting suspicious "friend requests" that might serve as a gateway to harmful content. Similarly, our immune system uses its own judgment to identify cellular "profiles" ...
Sep 20, 2023
0
26
Scientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein clearance within the brain. However, a new study published in Science has revealed that its essential ...
May 25, 2023
0
96
Cold activates a cellular cleansing mechanism that breaks down harmful protein aggregations responsible for various diseases associated with aging. In recent years, studies on different model organisms have already shown ...
Apr 3, 2023
0
344
