Enzymes: News and Research on Aldo-Keto Reductases

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New drug fails to improve diabetes-related heart failure

One of the first studies to attempt to treat early-stage heart failure in patients with Type 2 diabetes did not meet its primary endpoint, but a preplanned subgroup analysis found a statistically significant effect of treatment ...

Apr 8, 2024

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Aldose reductase promotes diet-induced obesity

High-fat diet (HFD) feeding in mice promotes induction of aldose reductase (AR) activity, expression, and senescence of adipocytes in subcutaneous adipose tissue (scAT), according to a new study in Obesity journal.

Jul 27, 2022

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