MeSH tree: G05.360.160.180
The human immunodeficiency virus HIV-1 is able to infect various tissues in humans. Once inside the cells, the virus integrates its genome into the cellular genome and establishes persistent infections. The role of the structure ...
Mar 16, 2023
0
91
A single cell contains 2-3 meters of DNA, meaning that the only way to store it is to package it into tight coils. The solution is chromatin: a complex of DNA wrapped around proteins called histones. In the 3D space, this ...
Mar 15, 2023
0
60
A new targeted drug has not only sparked remissions in patients with a common form of leukemia but also induced the cancer cells to reveal one of their schemes for resisting the drug, investigators at Dana-Farber Cancer Institute ...
Mar 15, 2023
0
74
Many diseases affect how cells are spatially organized in tissues, such as in Alzheimer's disease, where amyloid-β proteins clump together to form plaques in the brain. Studying how cells differ in various regions of tissue ...
Dec 8, 2022
0
64
Early life experiences can impact the activity of our genes much later on and even affect longevity, finds a new study in fruit flies led by UCL researchers.
Dec 1, 2022
0
116
Scientists at the Francis Crick Institute have uncovered how a build-up of DNA molecules can impact survival chances in people with severe COVID-19 or sepsis, and have developed a tool that could be used to identify the patients ...
Nov 17, 2022
0
83
The human heart is an intricate, complex organ and, like a car that starts sputtering, its function deteriorates for all sorts of reasons. Cardiomyopathy—any disease of the heart muscle that makes it pump blood less effectively—can ...
Oct 5, 2022
0
53
Progeroid syndromes are a group of rare genetic disorders that cause signs of premature aging in children and young adults, such as Werner Syndrome and Hutchinson Gilford Progeria Syndrome. Patients affected by progeroid ...
Oct 4, 2022
0
56
A new rodent study shows that even small quantities of alcohol can trigger epigenomic and transcriptomic changes in brain circuitry in an area that is crucial in the development of addiction.
Sep 12, 2022
0
55
