MeSH tree: C15.378.050.085.080.280
Alcohol consumption leads to the formation of a toxic compound called acetaldehyde, which damages DNA. A research team from IOCB Prague has now described in detail how cells repair this damaged genetic information.
Dec 16, 2025
0
49
Experts at Cincinnati Children's have uncovered striking metabolic differences in people with Fanconi anemia (FA), a rare genetic disorder that causes bone marrow failure and dramatically increases cancer risk.
Nov 28, 2025
0
11
An antibody treatment developed at Stanford Medicine successfully prepared patients for stem cell transplants without toxic busulfan chemotherapy or radiation, a Phase I clinical trial has shown.
Jul 22, 2025
1
401
A team of scientists from the San Raffaele-Telethon Institute for Gene Therapy (SR-Tiget) in Milan, Italy, has identified a unique window shortly after birth in which circulating blood stem cells can be effectively targeted ...
May 28, 2025
0
24
Fanconi anemia is an aggressive, life-threatening disorder. Most individuals living with this rare genetic condition, characterized by bone marrow failure and cancer predisposition, survive into adulthood only with bone marrow ...
May 8, 2025
0
0
"I just wish someone had told me this was a possibility." Kara Maxwell distinctly remembers the moment she heard those words eight years ago from the mother of a child with Fanconi anemia (FA). Maxwell met her at a conference ...
Jan 9, 2025
0
0
Fanconi anemia (FA) is a rare hereditary cancer predisposition disease characterized by bone marrow failure as well as endocrine and physical abnormalities. A key clinical feature in those affected is a high risk of cancer. ...
Jun 3, 2024
0
1
An international study led by researchers from Children's Hospital of Philadelphia (CHOP) has discovered an important biological cause of Fanconi anemia, a rare inherited disorder that almost universally leads to bone marrow ...
Mar 22, 2024
0
26
Published in the American Journal of Medical Genetics, a University of Minnesota Medical School study found that it is normal for children with Fanconi anemia to be shorter and thinner than other children. Fanconi anemia ...
Feb 26, 2024
0
0
Like the New York City subway system, the DNA in our cells needs to operate around the clock—and it's in constant need of repair. In any given cell at any given time, molecular processes are underway to seal cracks in the ...
Nov 30, 2022
0
31
