MeSH tree: C15.604.250
The first time Joey Carlsen Martinez came to Memorial Sloan Kettering Cancer Center (MSK), he was in terrible shape. He had a rare blood cancer called Erdheim-Chester disease, and his symptoms included crushing fatigue, severe ...
Oct 23, 2025
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Adding genomic sequencing to newborn blood screening would detect hundreds of additional childhood conditions, providing much earlier diagnosis and treatment, according to a new study. A baby's genome, which stays with them ...
Oct 9, 2025
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A study, led by experts at the University of Nottingham, has found that young people suffering from certain types of cancer, such as bone tumors, are experiencing lengthy times to diagnosis. The Childhood Cancer Diagnosis ...
May 28, 2025
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A nationwide team led by researchers at Baylor College of Medicine, Texas Children's Hospital and UPMC Children's Hospital of Pittsburgh has proposed a major revision to how Langerhans cell histiocytosis (LCH) is diagnosed ...
Apr 2, 2025
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Hemophagocytic lymphohistiocytosis (HLH) is a rare and often aggressive syndrome of hyperactive inflammation with up to a 40% mortality rate. Scientists at St. Jude Children's Research Hospital have shown that a drug inhibiting ...
Mar 6, 2024
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Some hereditary genetic defects cause an exaggerated immune response that can be fatal. Using the CRISPR-Cas9 gene-editing tool, such defects can be corrected, thus normalizing the immune response, as researchers led by Klaus ...
Feb 2, 2024
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Hemophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS) are life-threatening systemic hyperinflammatory syndromes. Systemic hyperinflammation and HLH/MAS can occur in nearly any inflammatory state, ...
Feb 1, 2024
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Four genetic variants have been identified that are associated with an increased risk for developing progressive multifocal leukoencephalopathy (PML), according to a study presented at the annual meeting of the American Neurological ...
Sep 19, 2023
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In humans, the SLC29A3 gene regulates the function of lysosomes to control waste recycling in cells such as macrophages (that engulf and destroy foreign bodies). This gene encodes for the lysosomal protein that transport ...
Aug 22, 2023
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The origins of the serious cancer-like disease Langerhans' Cell Histiocytosis (LCH) have been identified by researchers from Karolinska Institutet in collaboration with Karolinska University Hospital. The findings presented ...
Dec 16, 2022
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