Researchers discuss disrupting NKG2A:HLA-E interactions for enhanced anti-cancer immunity
A new editorial titled "Strategies to disrupt NKG2A:HLA-E interactions for improved anti-cancer immunity" has been published in Oncotarget.
Aug 21, 2024
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Immune System: News and Research on T-Lymphocytes, Cytotoxic
MeSH tree: A15.382.490.555.283.875
Drug bypasses suppressive immune cells to unleash immunotherapy
By recruiting the immune system to combat tumor cells, immunotherapy has improved survival rates, offering hope to millions of cancer patients. However, only about one in five people responds favorably to these treatments.
Aug 6, 2024
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Better together: Spatial arrangement of three immune cells is key to attacking tumors, study finds
There's a frustrating fact about today's immunotherapies for cancer. While sometimes they work beautifully—completely eliminating or greatly reducing cancer in particular patients—other times they don't work at all. It's ...
Jul 15, 2024
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Reinvigorating exhausted immune cells reveals potential therapy target for cancer
The ecosystem that surrounds a tumor, also known as the tumor microenvironment, includes immune cells, tissues, blood vessels and other cells that interact with each other and with the tumor. Over time, the tumor shapes this ...
Jun 13, 2024
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Researchers identify key differences in inner workings of immune cells
Cytotoxic T cells are an important component of the immune system. Once activated, they differentiate into either short-lived effector cells or long-lived memory cells. Studies by researchers at ETH Zurich have found that ...
Jun 6, 2024
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Researchers reveal uncharted liver-focused pathway in gene therapy immune responses
Indiana University School of Medicine researchers have uncovered vital insights regarding a liver trigger that blocks an undesired immune response from gene therapy, surprisingly resulting in activating specific immune cells ...
Dec 7, 2023
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Scar tissue holds hints about pancreatic cancer outcome, research finds
Scar tissue that forms around a growing pancreatic tumor called a pancreatic ductal adenocarcinoma harbors valuable clues as to how long people with these cancers are likely to live, according to a new study led by researchers ...
Nov 24, 2023
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T-cell receptor discovery has huge potential for engineering custom immune responses
T cells are soldiers on the front lines of the human immune system. They are responsible for many important roles, including attacking viral- or bacterial-infected cells and certain cancer cells, and immunological memory—remembering ...
Oct 25, 2023
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Drug mechanism opens door for new anti-cancer immunotherapies
Researchers have revealed a new mechanism of targeted drug treatment used against chronic lymphocytic leukemia, through the promotion of immune cell function, that could be exploited using new anti-cancer immunotherapies.
Oct 19, 2023
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New treatment trialed in mice offers hope for advanced liver cancer
Researchers have discovered a new way to treat hepatocellular carcinoma (HCC) the most common type of liver cancer, and the third leading cause of cancer death worldwide.
Sep 26, 2023
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