MeSH tree: C05.116.099.708
A new paper in Genome Biology and Evolution finds that the link between paternal age and rare congenital disorders is more complex than scientists had previously thought.
Feb 27, 2024
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105
A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as "brittle bone disease."
Jan 4, 2024
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40
For children with achondroplasia, vosoritide is associated with a gain in the change in height Z score from baseline and a mild adverse event profile, according to a study published in the January issue of The Lancet Child ...
Dec 30, 2023
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56
A drug that boosts bone growth in children with the most common form of dwarfism may also reduce their chances of sudden infant death syndrome, sleep apnea, and needing surgery, according to a new study.
Nov 21, 2023
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Teresa Quattrin, MD, University at Buffalo Distinguished Professor of pediatrics, is a co-author on a new global study that suggests a novel treatment option for children with achondroplasia—a form of severe short stature.
Nov 13, 2023
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75
Perhaps the most obvious feature of a neuron is the long branch called an axon that ventures far from the cell body to connect with other neurons or muscles. If that long, thin projection ever seems like it could be vulnerable, ...
Jun 12, 2023
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A clinical trial at the National Institutes of Health found that a medication, denosumab, significantly reduced abnormal bone turnover in adults with fibrous dysplasia, a rare disease marked by weak and misshapen bones. Bone ...
Apr 5, 2023
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81
People who suffer from back pain may get relief from research showing that electrical fields and fish genes provide novel building blocks for a healthy skeleton.
Feb 15, 2023
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A research team led by Hong Kong Baptist University (HKBU) has identified a molecular target for bone anabolic therapies using a selected aptamer that serves as an inhibitor of sclerostin, a protein that prevents bone growth. ...
Dec 19, 2022
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69
Two men buried long ago in a medieval graveyard in Co. Donegal had a genetic condition called multiple osteochondromas, which causes benign bone tumors. One of the disease mutations is a new discovery, so this is the first ...
Dec 5, 2022
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