Nervous System Diseases: News and Research on Malformations of Cortical Development, Group I

MeSH tree: C10.500.507.400

Lab-grown mini-brains shed light on childhood epilepsy

Why does the same genetic mutation cause a severe brain malformation in some patients but not in others? Researchers from the MOSAIC team at the Paris Brain Institute have developed mosaic human cortical organoids carrying ...

A curiosity-driven journey toward understanding brain folding

The human brain's soft folds and ridges, arising in early development and continuing through the first 18 months of life, are a visual icon for intelligence itself. Peeling back the layers of this fundamental biological process ...

How errors in the cytoskeleton lead to a smaller brain

Why do some children develop a brain that is too small (microcephaly)? An international research team involving the German Primate Center—Leibniz Institute for Primate Research (DPZ), Hannover Medical School (MHH), and the ...

How a gene shapes the architecture of the human brain

Researchers around the world are studying how the human brain achieves its extraordinary complexity. A team at the Central Institute of Mental Health in Mannheim and the German Primate Center—Leibniz Institute for Primate ...

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