MeSH tree: C10.500.507.400.125
Why does the same genetic mutation cause a severe brain malformation in some patients but not in others? Researchers from the MOSAIC team at the Paris Brain Institute have developed mosaic human cortical organoids carrying ...
Apr 16, 2026
0
4
For pediatric patients with drug-resistant focal epilepsy, stereoelectroencephalography-guided radiofrequency thermocoagulation (SEEG-RFTC) is safe, with favorable outcomes for most patients, according to a study published ...
Apr 1, 2026
0
3
Researchers have discovered that mutations in the FOXJ3 gene act as a "master switch" failure, disrupting how the brain builds its layers and leading to FCD, a primary cause of drug-resistant epilepsy. The study, published ...
Mar 9, 2026
0
8
Using a single-cell sequencing technique, Brazilian researchers have created the first cell atlas of focal cortical dysplasia (FCD), a malformation of the cerebral cortex that leads to drug-resistant epilepsy. These cases ...
Jan 30, 2025
0
31
UCL researchers have developed a new gene therapy to cure a devastating form of childhood epilepsy, which a new study shows can significantly reduce seizures in mice.
Dec 14, 2023
0
48
