MeSH tree: D13.150.650.700
In Huntington's disease, the mutant huntingtin gene (HTT) mRNA is retained in the nucleus and forms insoluble clusters. A new study shows that short interfering RNA (siRNA), an oligonucleotide therapeutic strategy that reduces ...
Jul 22, 2024
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Researchers at the Francis Crick Institute, UCL Great Ormond Street Institute for Child Health and Great Ormond Street Hospital for Children (GOSH) have designed a new genetic therapy that could alleviate debilitating giant ...
Jun 17, 2024
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Scientists at UC Riverside have demonstrated a new, RNA-based vaccine strategy that is effective against any strain of a virus and can be used safely even by babies or the immunocompromised.
Apr 15, 2024
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203
Cell division is the generative spark of nearly every lifeform on Earth. But if healthy growth goes unchecked, cell division can turn lethal, overwhelming the organism. Such is the case with so-called oncogenes. When altered ...
Mar 12, 2024
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Society learned about the value of mRNA during the COVID-19 pandemic when we saw scientists and medical professionals harness its power to deliver a vaccine for the virus within a year.
Feb 20, 2024
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A recent trial of a novel gene-editing technique that lowered dangerously high cholesterol by up to 55% has generated talk of a new front opening against cardiovascular disease, which kills nearly 700,000 Americans each year ...
Dec 13, 2023
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Researchers at UC Davis Comprehensive Cancer Center have shown that inhibiting a specific protein using gene therapy can shrink hepatocellular carcinoma (HCC) in mice. Silencing the galectin 1 (Gal1) protein, which is often ...
Nov 30, 2023
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Findings from a Phase I trial reported by a Cleveland Clinic physician show that a single dose of an experimental therapy produced greater than 94% reductions in blood levels of lipoprotein(a), a key driver of heart disease ...
Nov 13, 2023
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96
A new editorial paper titled "DISE, an ancient anti-cancer mechanism that senses mutational load in cancerous cells?" has been published in Oncotarget.
Oct 3, 2023
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New discoveries in the development of Alzheimer's disease in a study led by Professor Michael Glickman and Dr. Inbal Maniv from the Faculty of Biology at the Technion were published in Nature Communications.
Oct 3, 2023
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