MeSH tree: D02.522.223
When the hospital germ Pseudomonas aeruginosa infects the body, it uses the sugar-binding protein LecA to attach itself to human cells, invade them, and form so-called biofilms. LecA thus plays a central role in the development ...
Nov 26, 2025
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Researchers have identified a promising new strategy for treating alcohol use disorder (AUD). A novel study found that the dopamine-boosting drug tolcapone increases activity in the prefrontal cortex (PFC) during self-control ...
Aug 13, 2025
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The lab of The Wistar Institute's Jessie Villanueva, Ph.D., has identified a new strategy for attacking treatment-resistant melanoma: inhibiting the gene S6K2. The team has published their findings in a paper titled "Selective ...
Feb 5, 2025
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University of Alabama at Birmingham researchers have discovered that a genetic risk score can predict how Black individuals with hypertension respond to the blood pressure medication chlorthalidone and their likelihood of ...
The LENS trial has demonstrated that fenofibrate, a drug usually used to lower cholesterol, reduces the risk of progression of diabetic retinopathy by 27%. The results were announced at the American Diabetes Association Scientific ...
Jun 24, 2024
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Wistar researchers successfully tested a simple intervention that could unlock greater anti-tumor power in therapies that use T cells—an approach known as "cell-based therapy," which uses specially designed T cells to fight ...
Dec 13, 2023
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A dietary supplement developed by a UT Southwestern Medical Center researcher significantly reduced high blood sugar caused by a diuretic used to lower blood pressure while also correcting electrolyte imbalances, UTSW researchers ...
Nov 30, 2023
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Researchers from IBB-UAB have developed a second-generation molecule that significantly improves the stabilization and inhibition of the aggregation of proteins involved in Transthyretin Amyloidosis (ATTR), a group of minority ...
Oct 18, 2023
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A large Veterans Affairs (VA) clinical trial found that the blood pressure drug chlorthalidone (CTD) was not superior to hydrochlorothiazide (HCTZ) for the prevention of cardiovascular disease or non-cancer death.
Dec 15, 2022
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Two common diuretics used to control blood pressure had no difference in cardiovascular outcomes, including death, according to late-breaking science research presented today at the American Heart Association's Scientific ...
Nov 7, 2022
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