Urogenital Diseases: News and Research on Nephritis

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New biomarker for immunoglobulin A nephropathy identified

Immunoglobulin A (IgA) nephropathy is an autoimmune disease characterized by the deposition of circulating IgA-containing immune complexes (IgA-ICs) in the glomerular mesangium, leading to mesangial cell proliferation, enhanced ...

Approved IV drug reduces lupus symptoms, clinical trial finds

An already-approved IV drug significantly reduces the symptoms of lupus, a new clinical trial showed. More than three-quarters of lupus patients taking obinutuzumab (Gazvya) had a significant improvement in their symptoms ...

Possible therapeutic targets for kidney disease identified

Chronic kidney disease (CKD) is on the rise in the United States, with roughly 36 million adults estimated to have the condition. As more people develop the disease, researchers from the University of Missouri School of Medicine ...

Certain immune cell subtypes drive lupus, study finds

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by Weill Cornell Medicine ...

Study uncovers glomerular disease outcomes across the lifespan

New research reveals that contrary to conventional belief, primary glomerular diseases are not necessarily benign for children and young adults. In fact, some subsets of children and young adults may experience faster kidney ...

Simple urine test could transform kidney care

In a finding set to change the way disease is monitored, Chandra Mohan, an international expert and pioneer in lupus research at the University of Houston, is reporting that urine samples can indicate lupus nephritis in a ...

Preclinical study identifies genetic misfire in lupus

Cedars-Sinai investigators have identified a "molecular switch" on a gene strongly associated with the autoimmune disease lupus, which appears to propel immune cells into overdrive, attacking and damaging healthy tissues ...

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