MeSH tree: C12.950.419.570.363
Cedars-Sinai investigators have identified a "molecular switch" on a gene strongly associated with the autoimmune disease lupus, which appears to propel immune cells into overdrive, attacking and damaging healthy tissues ...
Oct 13, 2025
0
20
In lupus nephritis, attainment of complete renal response (CRR)/partial renal response (PRR) and lupus low disease activity state (LLDAS) is associated with best relapse-free survival, with independent associations seen with ...
Aug 14, 2025
0
25
At the time when patients with lupus, or systemic lupus erythematosus (SLE), are diagnosed, approximately 15% to 30% will already have the inflammation-caused kidney disease lupus nephritis, which compromises kidney function ...
Aug 5, 2025
0
14
The U.S. Food and Drug Administration has approved GSK's autoinjector of Benlysta (belimumab) for subcutaneous injection in patients ≥5 years of age with active lupus nephritis who are receiving standard therapy.
Jul 1, 2025
0
17
New 100-week data from the ongoing Phase I/II study of zigakibart, an investigational anti-APRIL monoclonal antibody, reinforce its potential as a disease-modifying treatment for IgA nephropathy (IgAN). Findings presented ...
Jun 5, 2025
0
14
For patients with active lupus nephritis, obinutuzumab, a humanized type II anti-CD20 monoclonal antibody plus standard therapy is more efficacious for providing a complete renal response than standard therapy alone, according ...
Feb 26, 2025
0
14
IgA nephropathy (IgAN) is an immune response disease affecting the filtering units of the kidneys. It is an intractable disease with a complex physiological process. Streptococcus mutans, a dental caries-causing bacterial ...
Dec 2, 2024
0
29
Chronic kidney disease (CKD) cases and deaths in women surged worldwide between 1990 and 2021, according to a study presented at Kidney Week, the annual meeting of the American Society of Nephrology, held from Oct. 23 to ...
Nov 1, 2024
0
20
The hepatitis E virus affects the liver. But infected liver cells secrete a viral protein that reacts with antibodies in the blood and may form complexes that can damage the filter structure of the kidneys, as researchers ...
Oct 31, 2024
0
12
Atrasentan is associated with a significant and clinically meaningful reduction in proteinuria compared with placebo in patients with immunoglobulin A (IgA) nephropathy, according to a study published online Oct. 25 in the ...
Oct 30, 2024
0
19
