MeSH tree: A05.810.453.324.359.372.650
The kidneys are vital organs that sustain life by filtering the blood and producing urine. This filtration process takes place in specialized structures called glomeruli, where podocytes play a crucial role by forming the ...
Feb 17, 2026
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Chronic kidney disease (CKD) affects more than 700 million people worldwide and is caused by genetic and environmental factors, as well as existing medical conditions. Known genetic risk factors for CKD include mutations ...
Oct 2, 2025
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University of Florence–led investigators report that estrogen-regulated renal progenitor cells shape pregnancy adaptation in mice with failure of estrogen receptor alpha signaling precipitating preeclampsia, maternal kidney ...
Researchers at the University of Tsukuba have developed a novel mouse model that allows them to induce dysfunction in only one kidney. Using this model, they uncovered the molecular mechanisms behind the "renal counterbalance" ...
Jun 24, 2025
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A research team from the Medical University of Vienna has investigated structural changes in kidneys of patients with hypertension and type 2 diabetes. The results show that high blood pressure can lead to abnormalities in ...
Mar 27, 2025
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Researchers are making strides in improving gene therapies for genetic diseases, particularly chronic kidney disease, using adeno-associated virus, or AAV, vectors. While AAV-based treatments have shown promise, delivering ...
Dec 31, 2024
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Acute kidney injury (AKI) often occurs as a result of ischemia, which is a condition in which blood flow to part of the body is restricted, depriving tissues of oxygen and nutrients. This damage is commonly followed by reperfusion ...
Dec 3, 2024
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In patients with chronic kidney disease, the loss of podocytes—part of the kidney's glomerular filtration barrier—causes irreversible disease progression. So far, physicians and researchers have found no way to effectively ...
Oct 31, 2024
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IgA nephropathy is an autoimmune kidney disease, and complement, a component of the innate immune system, plays a role in the condition's pathogenesis. Investigators have developed and tested a novel gene therapy that enters ...
Oct 28, 2024
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In a study published in Cell Stem Cell, USC scientists report significant progress in cultivating nephron progenitor cells (NPCs), the cells destined to form the kidney's filtration system, the nephrons. NPCs hold immense ...
Apr 30, 2024
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