Gout flare-ups rise sharply with certain foods: study

May 31, 2012
Gout flare-ups rise sharply with certain foods: study
Research found more attacks after high consumption of compounds called purines, especially from meat, seafood.

(HealthDay) -- Meat, seafood and other foods rich in compounds called purines are associated with a fivefold increased risk of immediate gout flare-ups, a new study shows.

Gout is a form of arthritis that often first occurs in the big toe. Anecdotal evidence has suggested that purine-rich foods can trigger gout attacks, but it hasn't been clear whether they cause immediate attacks.

The study included more than 600 patients with gout, most of whom were men and who had an average age of 54. The patients were followed for a year. During that time, the patients had a total of nearly 1,250 gout attacks, most of which occurred in the toe joints, said Dr. Yuqing Zhang and colleagues at the Boston University School of Medicine.

The average amount of dietary purines consumed during a two-day period without gout attacks was 1.66 grams, compared with 2.03 grams in the two days before an attack, according to a journal news release. Patients in the top 20 percent of purine consumption were nearly five times more likely to have a gout flare-up than those in the bottom 20 percent.

Animal sources of purines -- such as meat and seafood -- were associated with a much higher risk of a gout attack than plant sources, such as beans, peas, lentils, oatmeal, spinach, asparagus and mushrooms.

Not only do plant sources of purines have lower levels of the compounds, they also contain important nutrients and contribute to lowering , something promoted as a way to control gout, the researchers noted.

Other major dietary sources of purines include yeast and alcohol.

"Avoiding or reducing purine-rich , especially of animal origin, may help reduce the risk of recurrent gout attacks," the researchers concluded.

The study was published online May 30 in the journal .

Although the research showed an association between increased purine consumption and more frequent gout attacks, it did not prove a direct cause-and-effect relationship.

Explore further: Enriched skimmed milk may curb frequency of gout flare-ups

More information: The American Academy of Family Physicians has more about gout.

Related Stories

Enriched skimmed milk may curb frequency of gout flare-ups

January 24, 2012
A daily dose of skimmed milk, enriched with two components found in dairy products, may help to curb the frequency of painful gout flare-ups, indicates research published online in the Annals of the Rheumatic Diseases.

Dual-energy CT may be useful in evaluating the severity of gout, study suggests

April 30, 2011
The incidence of gout is on the rise and duel energy CT has the potential to allow non-invasive diagnosis of the disease, according to radiologists at the University of British Columbia, Vancouver General Hospital, in Vancouver, ...

Study finds CT scans can help detect gout cases traditional tests miss

November 6, 2011
X-ray images known as CT scans can help confirm gout in patients who are suspected of having the painful condition but receive negative results from traditional tests, a Mayo Clinic study has found. The type of CT scan analyzed, ...

Recommended for you

Old World monkeys could be key to a new, powerful rheumatoid arthritis therapy

November 16, 2017
In the quest for a new and more effective treatment for rheumatoid arthritis, researchers from the Keck School of Medicine of USC looked to a primate that mostly roams the land in Asia, the Middle East and Africa. It was ...

Study lists foods for fighting rheumatoid arthritis symptoms and progression

November 8, 2017
A list of food items with proven beneficial effects on the progression and symptoms of rheumatoid arthritis is provided in a new study published today in Frontiers in Nutrition. The authors suggest incorporating these foods ...

Prototype equipment can detect rheumatoid arthritis

September 28, 2017
According to a first clinical study published in the scientific journal Photoacoustics, the University of Twente and various European partners have designed a device that shows the difference between healthy fingers and arthritic ...

Improving the recognition of anxiety and depression in rheumatoid arthritis

August 28, 2017
A study conducted by Keele University shows that patients with rheumatoid arthritis who are also suffering with anxiety or depression may avoid talking to their GP about their mental health symptoms.

How you think about your arthritis makes a difference

August 24, 2017
(HealthDay)—How well you cope with knee arthritis depends a lot on your mental outlook, a new study suggests.

Treating arthritis with algae

August 23, 2017
Researchers at ETH Zurich, Empa and the Norwegian research institute SINTEF are pursuing a new approach to treating arthritis. This is based on a polysaccharide, a long-chain sugar molecule, originating from brown algae. ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.