Study finds that people with cystic fibrosis who live in deprived areas have worse health

January 29, 2013, University of Liverpool

A study by the University of Liverpool has found that people with Cystic Fibrosis (CF) who live in deprived areas have worse growth and lung function than people living in more advantaged areas.

Researchers at the University of Liverpool examined the medical records of more than 9,000 cystic fibrosis patients under 40 years old, from 1996 to 2009. They found that children and adults with CF who lived in the most disadvantaged areas in the UK had lower weight, height and (BMI) than those from more affluent areas.

They were also more likely to have worse lung function, and to pick up severe . These differences appeared early on in childhood and continued through to adulthood, but did not get any wider over time.

The study, which was funded by the Medical Research Council (MRC) and used data provided by the Cystic Fibrosis Trust, also looked at the treatments received by people with CF in the NHS. It found that the NHS takes this disadvantage into account and treats people from deprived areas more intensively. They were about twice as likely to be treated with and nutritional therapies, even after taking into account their worse health. However, they were less likely to be treated with inhaled treatments, such as DNase, and inhaled antibiotics.

Dr David Taylor-Robinson, from the Department of Public Health and Policy, said: "This is the first study to examine the relationship between deprivation and longitudinal outcomes in in the UK, which is of particular interest in the study of because it is a genetic disease and affects all equally.

"It is important that children with CF are not exposed to second-hand smoke, which is more common in deprived areas, and may explain some of the difference in early lung function. This study also shows that the health effects of deprivation appear very early in childhood, even for such as CF.

"We need to make sure that all children get the best possible start in life in order to reduce health inequalities."

The research is published in The Lancet Respiratory Medicine.

Explore further: Early cystic fibrosis lung disease detected by bronchoalveolar lavage and lung clearance index

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