New research shows anti-wrinkle cream chemical works

March 6, 2013, University of Reading

(Medical Xpress)—University of Reading researchers have found that a chemical used in some anti-wrinkle creams can nearly double the amount of the protein collagen needed to give skin its elasticity.

Due to competition in the cosmetic industry, evidence of the effectiveness of cosmetics is hard to find. The research team measured the effectiveness of a peptide called MatrixylTM on , a protein which repairs . They found that MatrixylTM can almost double the amount of collagen that the cells in our body produce, provided the concentration is high enough.

Professor Ian Hamley, from the University of Reading's Department of Chemistry, said: "Studies like this are very important for the consumer as cosmetic companies rarely publish their work so rivals can't copy their products. Our research, supported by a University studentship with some additional funding by the Engineering and Physical Sciences Research Council (EPSRC), shows that products with MatrixylTM will have skin-care benefits."

Collagen is the most abundant protein in mammals and constitutes a significant proportion of our connective tissue. It is thought that peptide-based treatments that stimulate the formation of collagen could be made to treat wounds and enhance , as well as be used for cosmetic applications.

"Collagen-based materials have immense potential in tissue engineering," continued Professor Hamley. "BBSRC has recently funded the team to investigate wound healing in battlefield applications, as part of a collaboration with the Defence Science and Technology Laboratory, part of the Ministry of Defence."

Research partner Dr Che Connon, Reader in Tissue Engineering and Cell Therapy at the University of Reading, is using collagen based materials in the development of and .

In 2011 Professor Hamley received a prestigious Royal Society Wolfson Research Merit Award as part of a scheme to keep Britain's top research scientists in the UK. His previous research has provided new insights into potential treatments for Alzheimer's disease, a degenerative and incurable form of dementia that afflicts millions of people worldwide.

"Collagen Stimulating Effect of Peptide Amphiphile C16-KTTKS on Human Fibroblasts" was published (with page numbers) on the Molecular Pharmaceutics website on Monday 4 March.

Related Stories

Recommended for you

In most surgery patients, length of opioid prescription, number of refills spell highest risk for misuse

January 17, 2018
The possible link between physicians' opioid prescription patterns and subsequent abuse has occupied the attention of a nation in the throes of an opioid crisis looking for ways to stem what experts have dubbed an epidemic. ...

Patients receive most opioids at the doctor's office, not the ER

January 16, 2018
Around the country, state legislatures and hospitals have tightened emergency room prescribing guidelines for opioids to curb the addiction epidemic, but a new USC study shows that approach diverts attention from the main ...

FDA bans use of opioid-containing cough meds by kids

January 12, 2018
(HealthDay)—Trying to put a dent in the ongoing opioid addiction crisis, the U.S. Food and Drug Administration on Thursday slapped strict new restrictions on the use of opioid-containing cold and cough products by kids.

Taking ibuprofen for long periods found to alter human testicular physiology

January 9, 2018
A team of researchers from Denmark and France has found that taking regular doses of the pain reliever ibuprofen over a long period of time can lead to a disorder in men called compensated hypogonadism. In their paper published ...

Nearly one-third of Canadians have used opioids: study

January 9, 2018
Nearly one in three Canadians (29 percent) have used "some form of opioids" in the past five years, according to data released Tuesday as widespread fentanyl overdoses continue to kill.

Growing opioid epidemic forcing more children into foster care

January 8, 2018
The opioid epidemic has become so severe it's considered a national public health emergency. Addiction to prescription painkillers, such as oxycodone and morphine, has contributed to a dramatic rise in overdose deaths and ...

1 comment

Adjust slider to filter visible comments by rank

Display comments: newest first

tekram
not rated yet Mar 06, 2013
A particular system, currently in widespread commercial use, is the peptide amphiphile (PA) C16–KTTKS with the trade name (registered to Sederma SA, France) of Matrixyl.

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.