Few breast cancer survivors maintain adequate physical activity despite benefits

April 17, 2013

Breast cancer survivors are among the women who could most benefit from regular physical activity, yet few meet national exercise recommendations during the 10 years after being diagnosed, according to a study by researchers at Fred Hutchinson Cancer Research Center. Prior studies and available evidence show a strong association between physical activity and reduced mortality, extended survival and higher quality of life among breast cancer survivors. With 2.9 million breast cancer survivors living in the U.S. and another 80,000 added annually, there is considerable interest in the factors that promote health and well-being among these women.

The current study, published online ahead of print in the journal Cancer Epidemiology, Biomarkers and Prevention, followed an ethnically diverse group of 631 ages 18-64 from New Mexico, Los Angeles County and western Washington for 10 years. Recreational was ascertained for each woman via interviews and questionnaires the year before diagnosis and again two, five, and 10 years after enrollment into the study.

Prior to diagnosis, 34 percent of the women met U.S. physical activity guidelines. This percentage remained unchanged two years later. The percentage of women who complied with the activity guidelines increased to 39.5 percent at five years but then dropped to 21.4 percent at 10 years. Overall, researchers found that fewer than 8 percent of the survivors met U.S. physical activity guidelines at all of the study time points.

U.S. physical activity guidelines call for at least 150 minutes per week of or at least 75 minutes per week of . Researchers focused on 16 recreational physical activities: fast walking, jogging, running, hiking, aerobics, bicycling, swimming, tennis, golf, skiing, Nordic track, fast dancing, bowling, rowing, horseback riding and light calisthenics.

"The recommends that exercise for at least 150 minutes per week. Most survivors may also benefit from strength training exercises at least two days per week," said Caitlin Mason, Ph.D., corresponding author and a postdoctoral research fellow in the Public Health Sciences Division at Fred Hutch. "For survivors who have not been previously active, we advise that they gradually work up to these recommendations," she said.

The researchers were surprised by the large drop in activity between five- and 10-year follow-up. After taking into account factors such as age and body size at diagnosis, the study found no other personal characteristics or aspects related to the type of or its treatment were significantly associated with the drop in activity between the five- and 10-year reporting periods.

"It seems unlikely that this pattern reflects aging alone given the consistency and magnitude of the trend across all age groups," the authors wrote. "Whether this reflects a cohort effect or a unique aspect of the cancer survivorship experience is unclear."

All of the women were enrolled in the HEAL (Health, Eating, Activity and Lifestyle) Study, which investigates methods to improve breast cancer survival.

Senior author Anne McTiernan, Ph.D., a member of the Public Health Sciences Division at Fred Hutch, is principal investigator of the multi-site study.

The HEAL Study cohort represents one of the few breast cancer survivor groups that has repeated assessments of physical activity for as long as a decade after diagnosis. The authors acknowledge that levels of inactivity may be underestimated because the women included in the study tended to be a bit younger and were less likely to smoke, have advanced disease or have limits to doing physical activity compared to survivors who were not followed for 10 years. The predictors of physical activity in this population remain poorly understood, according to the authors.

"Our inability to identify many significant predictors of long-term physical activity participation suggests that the factors influencing physical activity behaviors in breast cancer survivors are complex and may differ from those in the general population," the authors wrote. "Additional consideration of psychosocial factors and issues related to pain management, fatigue, and specific treatment effects may help to better understand the unique issues faced by cancer survivors and their impact on participation."

Explore further: Physical activity linked to reduced mortality in breast and colon cancer patients

More information: "Long-term physical activity trends in breast cancer survivors" Cancer Epidemiology, Biomarkers and Prevention, 2013.

Related Stories

Physical activity linked to reduced mortality in breast and colon cancer patients

May 8, 2012
Physical activity is associated with reduced breast and colon cancer mortality, but there is insufficient evidence on the association for other cancer types, according to a study published May 8 in the Journal of the National ...

Time spent watching television is not associated with death among breast cancer survivors

January 31, 2013
Spending a lot of time watching television after breast cancer diagnosis is not linked to death in these breast cancer survivors. It appears that after accounting for self-reported physical activity levels after diagnosis, ...

Physical activity cuts mortality in colorectal cancer survivors

January 23, 2013
(HealthDay)—For patients with invasive, non-metastatic colorectal cancer, increased recreational physical activity is associated with reduced all-cause mortality, while prolonged sedentary time correlates with increased ...

Recommended for you

New therapeutic approach for difficult-to-treat subtype of ovarian cancer identified

July 24, 2017
A potential new therapeutic strategy for a difficult-to-treat form of ovarian cancer has been discovered by Wistar scientists. The findings were published online in Nature Cell Biology.

Anti-cancer chemotherapeutic agent inhibits glioblastoma growth and radiation resistance

July 24, 2017
Glioblastoma is a primary brain tumor with dismal survival rates, even after treatment with surgery, chemotherapy and radiation. A small subpopulation of tumor cells—glioma stem cells—is responsible for glioblastoma's ...

Immune cells the missing ingredient in new bladder cancer treatment

July 24, 2017
New research offers a possible explanation for why a new type of cancer treatment hasn't been working as expected against bladder cancer.

No dye: Cancer patients' gray hair darkened on immune drugs

July 21, 2017
Cancer patients' gray hair unexpectedly turned youthfully dark while taking novel drugs, and it has doctors scratching their heads.

Shooting the achilles heel of nervous system cancers

July 20, 2017
Virtually all cancer treatments used today also damage normal cells, causing the toxic side effects associated with cancer treatment. A cooperative research team led by researchers at Dartmouth's Norris Cotton Cancer Center ...

Immune-cell numbers predict response to combination immunotherapy in melanoma

July 20, 2017
Whether a melanoma patient will better respond to a single immunotherapy drug or two in combination depends on the abundance of certain white blood cells within their tumors, according to a new study conducted by UC San Francisco ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.