HIV 'cure' looks 'promising,' Danish scientists contend

April 29, 2013
HIV 'Cure' looks 'Promising,' danish scientists contend
They're working on human trials designed to make it easier to attack AIDS-causing virus, according to published reports.

(HealthDay)—Danish scientists testing a novel HIV treatment in human trials contend that they're confident their strategy will result in a cure for the AIDS-causing virus, according to news reports.

The technique—already tested successfully in lab experiments—involves freeing the from DNA cells, where it collects in "," and bringing it to the surface of the cells, the Telegraph in Great Britain reported. Once the virus has surfaced, it can be permanently destroyed by a "vaccine" that primes the body's natural , the researchers said.

"I am almost certain that we will be successful in releasing the reservoirs of HIV," said Dr. Ole Sogaard, a senior researcher at the Aarhus University Hospital in Denmark, according to the news report. So far the are "promising," he said.

Human clinical trials are under way, said Sogaard, adding that early signs are "promising. I am almost certain that we will be successful in releasing the reservoirs of HIV," he said.

Fifteen patients are currently taking part in the trials, and if they are found to have successfully been cured of HIV, the "cure" will be tested on a wider scale, the Telegraph reported.

"The challenge will be getting the patients' immune system to recognize the virus and destroy it. This depends on the strength and sensitivity of individual immune systems," Sogaard said, the newspaper reported.

Sogaard said a "cure" is different than a preventative vaccine. That means continued awareness of unsafe behaviors—such as avoiding or sharing needles for intravenous drug use—is still the key to combating HIV.

If the Danish researchers are successful, it would obviously represent a huge step in the battle against HIV.

A large study of an experimental was halted recently because the shots weren't preventing infection, the U.S. National Institutes of Health said last week.

The clinical trial included about 2,500 people, mostly gay men, in 19 cities. Half of the participants were given the vaccine developed by the NIH and half received placebo shots. A safety review found that slightly more people who had received the vaccine later became infected with HIV. The reasons for this aren't clear.

While the vaccinations are being stopped, the NIH said it will continue to track the study participants' health, the Associated Press reported.

Numerous attempts to develop an HIV/AIDS vaccine have failed.

Explore further: Latest HIV vaccine doesn't work; govt halts study (Update)

More information: To learn more about HIV, visit the U.S. National Library of Medicine.

Related Stories

Latest HIV vaccine doesn't work; govt halts study (Update)

April 25, 2013
The latest bad news in the hunt for an AIDS vaccine: The government halted a large U.S. study on Thursday, saying the experimental shots are not preventing HIV infection.

Adaptive trial designs could accelerate HIV vaccine development

April 20, 2011
In the past 12 years, four large-scale efficacy trials of HIV vaccines have been conducted in various populations. Results from the most recent trial—the RV144 trial in Thailand, which found a 31 percent reduction ...

Scientists probe how some HIV patients resist AIDS

October 1, 2012
(HealthDay)—Researchers who discovered an immune system mechanism that seems to provide some people with a natural defense against HIV say their finding could help efforts to develop a vaccine for HIV/AIDS.

Harnessing immune cells' adaptability to design an effective HIV vaccine

March 21, 2013
In infected individuals, HIV mutates rapidly to escape recognition by immune cells. This process of continuous evolution is the main obstacle to natural immunity and the development of an effective vaccine. A new study published ...

Recommended for you

New injectable antiretroviral treatment proved to be as effective as standard oral therapy

August 3, 2017
Intramuscularly administered antiretroviral therapy (ART) may be as effective for HIV treatment as current oral therapies. This is the main conclusion of a Phase II clinical trial carried out by 50 research centers around ...

Research finds home-based kit would increase HIV testing

July 31, 2017
Research led by William Robinson, PhD, Associate Research Professor of Behavioral & Community Health Sciences at LSU Health New Orleans School of Public Health, has found that 86% of heterosexuals who are at high risk for ...

Scientists divulge latest in HIV prevention

July 25, 2017
A far cry from the 1990s "ABC" campaign promoting abstinence and monogamy as HIV protection, scientists reported on new approaches Tuesday allowing people to have all the safe sex they want.

Girl's HIV infection seems under control without AIDS drugs

July 24, 2017
A South African girl born with the AIDS virus has kept her infection suppressed for more than eight years after stopping anti-HIV medicines—more evidence that early treatment can occasionally cause a long remission that, ...

Meds by monthly injection might revolutionize HIV care (Update)

July 24, 2017
Getting a shot of medication to control HIV every month or two instead of having to take pills every day could transform the way the virus is kept at bay.

Candidate AIDS vaccine passes early test

July 24, 2017
The three-decade-old quest for an AIDS vaccine received a shot of hope Monday when developers announced that a prototype triggered the immune system in an early phase of human trials.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.