Sleep-disordered breathing in REM linked to insulin resistance

Sleep-disordered breathing in REM linked to insulin resistance
(HealthDay)—The correlation between sleep-disordered breathing (SDB) and glucose metabolism varies for rapid eye movement (REM) sleep and non-REM sleep, according to a study published in the Nov. 1 issue of the American Journal of Respiratory and Critical Care Medicine.

Hassan A. Chami, M.D., from the American University of Beirut, and colleagues characterized the association between REM-related SDB, , and insulin resistance in a community-based sample of 3,310 participants. The apnea-hypopnea index (AHI) was used to quantify SDB severity during REM (AHIREM) and non-REM (AHINREM) sleep. A glucose tolerance test assessed fasting and two-hour post-challenge glucose levels in 2,264 participants; the homeostatic model assessment index for insulin resistance (HOMA-IR) was measured for 1,543 participants.

The researchers found that in models that adjusted for age, sex, race, and site, AHIREM and AHINREM correlated with fasting glycemia, postprandial glucose levels, and HOMA-IR. AHIREM was only associated with HOMA-IR and AHINREM was only associated with fasting and postprandial glucose levels after further adjustment for body mass index, waist circumference, and sleep duration.

"AHIREM is associated with but not with fasting glycemia or glucose intolerance," the authors write.


Explore further

Sleep affects HOMA-IR in overweight, obese teens

More information: Full Text (subscription or payment may be required)

Copyright © 2015 HealthDay. All rights reserved.

Citation: Sleep-disordered breathing in REM linked to insulin resistance (2015, November 5) retrieved 20 May 2019 from https://medicalxpress.com/news/2015-11-sleep-disordered-rem-linked-insulin-resistance.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
4 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more