Hyaluronic acid, autologous fat augment nasolabial folds

March 20, 2017

(HealthDay)—Hyaluronic acid (HA) and autologous fat are both beneficial for augmentation of nasolabial folds (NLFs), according to a study published online March 14 in the Journal of Cosmetic Dermatology.

Xiaogen Hu, M.D., from the China Japan Friendship Hospital in Beijing, and colleagues examined the effectiveness and safety of correction of the NLF in a randomized study. Fifty-seven patients were randomized to receive injections of HA or autologous fat in both NLFs. Efficacy was assessed using evaluation of final improvement by blinded evaluator and patient-self using photographs.

The researchers found that within nine months there were no significant differences between the two methods in the blinded evaluator scores for NLF in accordance with the Wrinkle Severity Rating Scale. At 12-month follow-up there was a statistically between the groups favoring the use of autologous fat. The results were similar for subjects' self-assessment and the evaluator scores. In the early stages of recovery there was a higher rate of reactions at the injection site for the fat group compared with the HA group, while in later stages the adverse events were similar.

"Both HA gel and autologous fat provide augmentation of NLFs," the authors write. "The magnitude and duration of NLF correction appear to be similarly effective and safe within a period."

Explore further: Monophasic HA filler plus lidocaine corrects nasolabial folds

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Platelet-rich plasma injection reduces facial wrinkles

August 8, 2016

(HealthDay)—Platelet-rich plasma (PRP) intradermal injection can reduce wrinkles, especially wrinkles of the nasolabial folds (NLFs), according to a study published online July 29 in the Journal of Cosmetic Dermatology.

Polycaprolactone efficient for nasolabial fold treatment

January 15, 2015

(HealthDay)—For patients with nasolabial folds (NLFs), treatment with a novel biostimulatory polycaprolactone (PCL)-based dermal filler is associated with improved long-lasting efficacy compared with nonanimal stabilized ...

Autologous urethral sling no benefit after prostatectomy

January 19, 2017

(HealthDay)—Placement of a retropubic urethral sling fashioned from autologous vas deferens during robotic assisted radical prostatectomy does not improve recovery of continence, according to a study published in the February ...

Recommended for you

New way of screening potential treatments for tuberculosis

March 29, 2017

Scientists from LSTM's Research Centre for Drugs and Diagnostics (RCDD) have described in a paper published today in Scientific Reports, a new way of screening potential treatments for Tuberculosis (TB) which may assist in ...

Discovery may help patients beat deadly pneumonia

March 28, 2017

Researchers have found that a hormone responsible for controlling iron metabolism helps fight off a severe form of bacterial pneumonia, and that discovery may offer a simple way to help vulnerable patients.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.