Actemra approved for certain blood vessel inflammation

(HealthDay)—The injected drug Actemra (tocilizumab) has been approved by the U.S. Food and Drug Administration to treat adults with giant cell arteritis, an inflammation of the blood vessels (vasculitis).

In a media release Monday, the FDA said this form of vasculitis mostly involves of the head. Traditional therapy includes large doses of called corticosteroids.

"We expedited the development and review of this application because [Actemra] fulfills a critical need for patients with this serious disease who had limited treatment options," said Dr. Badrul Chowdhury, director of the agency's Division of Pulmonary, Allergy, and Rheumatology Products.

Actemra was evaluated in clinical studies involving 251 people with . The drug will carry a boxed label warning of the possibility of serious infections. For that reason, live vaccines should be avoided while taking the drug, the FDA said.

And Actemra should be used "with caution" among people at increased risk of gastrointestinal perforation or dangerous allergic-like hypersensitivity reactions, the agency added.

The Hoffman La Roche drug was first approved in 2010 for moderately-to-severely active rheumatoid arthritis. The company is based in Basel, Switzerland.


Explore further

Siliq approved for plaque psoriasis

More information: Learn more from the FDA.

Copyright © 2017 HealthDay. All rights reserved.

Citation: Actemra approved for certain blood vessel inflammation (2017, May 22) retrieved 17 January 2021 from https://medicalxpress.com/news/2017-05-actemra-blood-vessel-inflammation.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
0 shares

Feedback to editors

User comments