Ultrasound findings correlate with inflammatory myopathies

August 11, 2017

(HealthDay)—Ultrasonography findings seem to correlate well with the disease activity of idiopathic inflammatory myopathies (IIMs), and may be a useful tool for patient evaluation, according to a study published online Aug. 7 in the International Journal of Rheumatic Diseases.

Joana Sousa Neves, M.D., from the Hospital Conde de Bertiandos in Ponte de Lima, Portugal, and colleagues evaluated 15 IIM (from 2005 to 2015). Patients had a mean age of 52.2 ± 22.09 years and mean duration of 4.6 ± 3.20 years. Assessments included a physical examination, muscle strength tests, laboratory analysis, and a selective muscle ultrasonography assessment.

The researchers found that nine of the 15 patients were in clinical remission, and ultrasonography revealed a preserved muscle pattern. In one patient with longstanding polymyositis with proximal weakness, symmetrical proximal muscle atrophy was found. In the remaining five patients, inflammation and focal or generalized muscle edema were present with muscular weakness, suggesting active disease. One of these patients in acute flare presented with atrophy changes plus edema. An additional patient had early untreated myositis with moderate power Doppler signal.

"As far as muscle ultrasonography assessment is concerned, a single specific pattern was not observed in our study. A mixture of edema and atrophy was detected depending on disease activity and duration," the authors write. "Ultrasonography findings seem to correlate well with , suggested by clinical data, and may be a useful tool to complement patient evaluation."

Explore further: Ultrasound IDs disease activity in rheumatoid arthritis

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Ultrasound IDs disease activity in rheumatoid arthritis

February 15, 2017
(HealthDay)—A 12-joint ultrasound (US) evaluation is relevant in determining disease activity in rheumatoid arthritis patients, according to a study published online Feb. 9 in the International Journal of Rheumatic Diseases.

Ultrasonography can guide drug modification in arthritis

August 26, 2016
(HealthDay)—Ultrasonography can be useful for guiding modification of anti-rheumatic drugs and steroids for patients with inflammatory arthritis (IA), according to a study published online Aug. 19 in the International Journal ...

Once-weekly steroid dosing can promote muscle repair without atrophy

May 8, 2017
Glucocorticoid steroids are used to treat a variety of conditions, including chronic inflammatory diseases and autoimmune diseases. Their effects on muscle recovery and repair make them particularly effective therapies for ...

Gene transfer corrects severe muscle defects in mice with Duchenne muscular dystrophy

July 27, 2017
Duchenne muscular dystrophy is a rapidly progressive disease that causes whole-body muscle weakness and atrophy due to deficiency in a protein called dystrophin. Researchers at the University of Missouri, National Center ...

Multifactorial mechanisms underlie leg weakness in hip OA

August 9, 2012
(HealthDay) -- Multiple factors contribute to leg weakness in people with hip osteoarthritis (OA), with muscle atrophy being the strongest contributor, according to the results of a systematic review published online July ...

Atrophy seen in gluteus maximus post gluteal augmentation

March 6, 2015
(HealthDay)—The gluteus maximus muscle presents atrophy after gluteal augmentation surgery with implants, according to a study published in the March issue of Plastic and Reconstructive Surgery.

Recommended for you

Breakthrough treatment for crippling jaw disease created

June 20, 2018
A first-ever tissue implant to safely treat a common jaw defect, known as temporomandibular joint dysfunction, has been successfully tested by UCI-led researchers in a large animal model, according to new findings.

Cell-free DNA profiling informative way to monitor urinary tract infections

June 20, 2018
Using shotgun DNA sequencing, Cornell University researchers have demonstrated a new method for monitoring urinary tract infections (UTIs) that surpasses traditional methods in providing valuable information about the dynamics ...

New flu vaccine only a little better than traditional shot

June 20, 2018
A newer kind of flu vaccine only worked a little bit better in seniors this past winter than traditional shots, the government reported Wednesday.

Blood signature could improve early tuberculosis diagnosis

June 19, 2018
A gene signature in the bloodstream could reveal whether someone is going to develop active tuberculosis (TB) disease months before symptoms begin. Such a signature has now been developed by a team led by the Francis Crick ...

Scientists uncover a factor important for Zika virus host species restriction

June 19, 2018
Princeton University researchers Qiang Ding, Alexander Ploss, and colleagues have identified one of the mechanisms by which Zika virus (ZIKV) circumvents immune control to replicate in human cells. The paper detailing this ...

Toothpaste and hand wash may contribute to antibiotic resistance

June 19, 2018
A common ingredient in toothpaste and hand wash could be contributing to antibiotic resistance, according to University of Queensland research.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.