Getting a grip on better health

Getting a grip on better health
Credit: Pixabay

Men with muscles like a young Arnold Schwarzenegger or a top weightlifter look powerful but a handshake will give away whether they're a healthy specimen—or at risk of a chronic disease or premature aging, experts say.

Medical researchers in South Australia, led by respiratory and sleep expert Professor Robert Adams, assessed more than 600 men aged over 40 to 88 years in the Men, Androgen, Inflammation, Lifestyle, Environment, and Stress (MAILES) study to measure the link between sleep apnea and mass with grip strength.

Chief investigator of the study, Flinders University Professor Adams, says no matter how much muscle mass, a simple grip test can highlight underlying issues connected with aging, systemic inflammation and worsening hypoxemia (lack of oxygen in the blood).

"Without good levels of oxygen in the blood, we cannot use the muscles we have to their maximum," says Professor Adams.

"Our findings suggest impairments in hand grip strength (HGS) may be related to fat infiltration of muscle, hypoxemia-induced reductions in peripheral neural innervation, or even endothelial dysfunction—a risk in chronic inflammation and even cancer," Professor Adams and colleagues conclude in a paper in open access journal Nature and Science of Sleep.

"Further studies are required to connect the common sleep problem obstructive sleep apnoea (OSA) with hypoxemia."

OSA is a common problem which involves repeated episodes of partial or complete obstruction of the throat during sleep which can cause breathing to slow down or stop leading to a fall in blood oxygen levels fall as a result.

Lead author of the paper, Adelaide Sleep Institute for Sleep Health researcher Dr. David Stevens, says overnight sleep studies of men aimed to link OSA sleep patterns with muscle and fat mass, and in turn grip strength.

"After allowing for health and lifestyle (exercise, smoking and underlying health conditions), it was clear that worsening hypoxemia, which included how much time was spent below 90% oxygen saturation (usually 97%) – and even how long people spent with their airways completely closed (known as apnea) – was associated with reduced —regardless of ," Dr. Steven says.

"This is important as up until now, age related declines in strength and immobility (sarcopenia) were thought to be due to reductions in muscle which started when someone was over 60 years old. Instead, the declines in strength appear to begin at a younger age in people with obstructive (OSA)," he says.

"Furthermore, considering that over a quarter of the MAILES participants have moderate to severe OSA, this suggests a large proportion of the population are at risk of early reductions in ."

Further studies of followup sleep studies will test for potential mechanisms to explain the results of the study, Dr. Stevens says.

"We recommend that more research be done to further explore the relationship between OSA, body composition, and HGS."

The new research paper, "Associations of OSA and Nocturnal Hypoxemia with Strength and Body Composition in Community Dwelling Middle Aged and Older Men," has been published in open journal Nature and Science of Sleep.


Explore further

Link between sleep apnea and increased risk of dementia

More information: David Stevens et al.

Associations of OSA and Nocturnal Hypoxemia with Strength and Body Composition in Community Dwelling Middle Aged and Older Men

, Nature and Science of Sleep (2020). DOI: 10.2147/NSS.S276932
Journal information: Nature and Science of Sleep

Citation: Getting a grip on better health (2020, November 30) retrieved 3 March 2021 from https://medicalxpress.com/news/2020-11-health.html
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