The role of the bilateral motor cortices in speech perception

Understanding how the motor cortex is involved in active inference of speech perception and decisions is important to understanding human language intelligence, which may inspire the next generation of AI. However, three key questions regarding the role of the bilateral motor cortices in speech perception remain unanswered.

Is the laryngeal motor cortex (LMC) engaged in speech perception in addition to production? How do bilateral motor cortices cooperate under varying degrees of difficulty? What specific stages of the perceptual decision-making process are modulated by the bilateral motor cortices?

In a study published in Nature Communications, a research team led by Dr. Du Yi at the Institute of Psychology of the Chinese Academy of Sciences found that the bilateral LMCs in the human brain are causally engaged in multiple stages of speech perception decision-making, and that the LMC engagement is left-dominant and particularly aids auditory processing in scenarios with perceptual challenges.

The researchers conducted two experiments. They delivered repetitive transcranial magnetic stimulation (rTMS) in Experiment 1 and theta-burst stimulation (TBS) in Experiment 2 to the left/right motor cortex of healthy Mandarin adult speakers to investigate if the categorical perceptual decision of lexical tone and plosive consonant with/without noisy background would be modulated accordingly. To localize the production-related dorsal LMC (dLMC) and TMC, participants underwent a functional magnetic resonance (fMRI) pretest where they performed phonation and tongue movement tasks.

Then the researchers applied two independent data-analysis pipelines to investigate the TBS modulation effects upon dLMC on behavioral responses in Experiment 2. To detect changes in perceptual sensitivity, they fitted psychometric curves to investigate modulations on the curve slope. To evaluate changes at specific stages of perceptual decision, they applied the hierarchical Bayesian estimation of the drift-diffusion model (HDDM) to disentangle what latent dynamic decision processes would be altered.

Psychometric curve slope analyses showed that cTBS upon bilateral dLMC affected both tone and consonant perception: cTBS upon the left dLMC inhibited tone perception in noise, and inhibited consonant perception in both quiet and noise; cTBS upon the right dLMC inhibited consonant perception in noise but not in quiet, and did not affect tone perception.

HDDM analyses showed that for all conditions except tone perception in quiet by left dLMC stimulation, cTBS significantly broadened the boundaries of decision-making; cTBS upon left dLMC affected evidence accumulation rates but right dLMC stimulation failed to exert similar effects; cTBS upon both left and right dLMC affected response biases consonant perception in noise.

The results revealed an effector-specific involvement of bilateral dLMC in perceptual decision of both lexical tone and voicing of plosive consonant, suggesting that the human LMC is causally engaged in speech perception as in speech production. They also provided evidence for the redundancy and functional reorganization of neural networks as the left dLMC plays a dominant role, while the right counterpart is only crucial in challenging tasks. Moreover, the specific perceptual decision stages that are modulated by the dLMC hinge on the hemisphere and task difficulty.

"In speech perception, our articulatory motor cortex acts like a denoiser that predicts the upcoming words by simulating the embedded motor gestures. Our study provides important empirical evidence to support that bilateral laryngeal motor cortices, the motor subregions essential for voicing and pitch control, are also parts of such denoiser systems," said Dr. Du, the corresponding author of this study.

This study expanded the knowledge of the underlying mechanisms and temporal dynamics of bilateral motor engagement in speech perceptual decision-making. It holds implications for the clinical translational research for speech disorder rehabilitation, as well as for the development of more robust AI algorithms with dynamical adaptivity.