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Oncology & Cancer
An AI-powered pipeline for personalized cancer vaccines
Ludwig Cancer Research scientists have developed a full, start-to-finish computational pipeline that integrates multiple molecular and genetic analyses of tumors and the specific molecular targets of T cells and harnesses ...
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Medical research news
Study shows key brain protein can impact behavior in mice
Researchers at the University of Kentucky were part of a team that discovered a key protein in the brain that can regulate motivation for reward in mice.
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Possible trigger of Crohn's disease discovered: Dysfunctional mitochondria disrupt the gut microbiome
Disruptions of mitochondrial functions have a fundamental influence on Crohn's disease. This connection has now been demonstrated by researchers at the Technical University of Munich (TUM). In a study published in Cell Host ...
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A potential non-invasive stool test and novel therapy for endometriosis
Promising findings by researchers at Baylor College of Medicine and collaborating institutions could lead to the development of a non-invasive stool test and a new therapy for endometriosis, a painful condition that affects ...
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Researchers find cord blood cells can build a better human immune system into mice
Immunity plays a central role in the fight against cancer. Many of the current immunotherapies aim at helping the patient's immune system to better recognize cancer cells—by using engineered antibodies—or by simply providing ...
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Typhoid vaccine trial confirms sustained protection for older children
A single dose of typhoid conjugate vaccine (TCV) offers safe, effective protection against typhoid two years after vaccination in all children, and sustained protection for older children at three to five years post immunization, ...
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New study identifies genetic changes in brain development that may contribute to schizophrenia
A collaborative study between researchers at the Icahn School of Medicine at Mount Sinai and Harvard Medical School has identified genetic mutations that occur during brain development and may contribute to the development ...
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Cancer drug could be used to save the limbs of peripheral artery disease patients, pre-clinical study suggests
Researchers at the Heart Research Institute (HRI) have made a new discovery, finding an existing drug used to kill tumor cells in cancer patients could also be used to save the limbs of patients with blocked arteries in their ...
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Brain cell connectivity research provides a potential target for anxiety disorders
Scientists at Université de Montréal and its affiliated Montreal Clinical Research Institute (IRCM) have uncovered unique roles for a protein complex in the structural organization and function of brain cell connectivity, ...
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Protein blocking bone development could hold clues for future osteoporosis treatment
Scientists have identified a protein that blocks the activity of bone-forming cells (osteoblasts) by stopping them from maturing during the journey to sites of bone formation.
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Researchers clarify role of VGLL3 in DNA double-strand break repair and chemotherapy
A research group led by Prof. Guo Caixia from the Beijing Institute of Genomics of the Chinese Academy of Sciences (CAS) and Tang Tie-Shan from the Institute of Zoology of CAS have discovered that VGLL3 modulates chemosensitivity ...
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One in three cases of oral cancer are due to smokeless tobacco, study reveals
A new study by the International Agency for Research on Cancer (IARC), with contribution from Karolinska Institutet, has revealed that one in three cases of oral cancer globally is linked to smokeless tobacco and areca nut ...
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Different types of teenage friendships critical to well-being as we age, scientists find
Being a teenager is hard, confusing—and crucially important. Scientists studying teenage socializing have found that teenage friendships could lay essential foundations for well-being in later life, and that not just the ...
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Breakdancers may risk 'headspin hole' caused by repetitive headspins, doctors warn
Breakdancers may be at risk of developing a condition caused by repeatedly doing a cardinal move of their practice and performance—the headspin—warn doctors in the journal BMJ Case Reports.
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Natural killer cells that live in the lungs can rapidly respond to a sugar rush, making them especially effective
Trinity College Dublin researchers based at St James's Hospital have provided important insights into the behavior and metabolic function of a previously largely unknown but crucial natural killer (NK) immune cell resident ...
19 hours ago
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Disrupting Asxl1 gene prevents T-cell exhaustion to improve immunotherapy, researchers discover
Immunotherapy, using a patient's own immune system to treat disease, has shown promise in some patients with cancer but has not worked in most. New research from St. Jude Children's Research Hospital and colleagues has found ...
19 hours ago
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Bilingualism may make the brain more efficient, especially when learned at a young age
Neuroplasticity is the brain's ability to build connections within itself, adapting to the surrounding environment. The brain is most plastic in childhood, forming new pathways in reaction to stimuli such as language.
21 hours ago
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Magnetically regulated gene therapy tech offers precise brain-circuit control
A new technology enables the control of specific brain circuits non-invasively with magnetic fields, according to a preclinical study from researchers at Weill Cornell Medicine, The Rockefeller University and the Icahn School ...
21 hours ago
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New study challenges longstanding assumption about the cause of the genome's most common mutation
A Ludwig Cancer Research study has punctured a longstanding assumption about the source of the most common type of DNA mutation seen in the genome—one that contributes to many genetic diseases, including cancer.
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