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Common arthritis pill repurposed to boost hair regrowth in alopecia patients

Upadacitinib is a medication widely used for the treatment of rheumatoid arthritis that works by inhibiting Janus kinase (JAK) enzymes, which are involved in signaling pathways that regulate immune responses. Now, scientists ...

Experimental pill targets nerve pain pathway, cutting opioid use after abdominal surgery

Opioids can be highly effective at relieving moderate to severe pain, whether it comes from surgery, an injury or conditions such as cancer. They work by activating opioid receptors in the brain and body, which block pain ...

Medical research news

Laser therapy offers weapon against deadly brain tumors

For patients facing a diagnosis of glioblastoma—one of the most aggressive and devastating forms of brain cancer—the standard path forward has long meant invasive open-skull surgery and a daunting prognosis.

Flexible brain circuits can switch between different tasks

As we move through everyday life, our brains engage in a huge variety of cognitive tasks. For example, during a grocery run, we might have to recall the items for a recipe, remember where the clerk said the flour was located ...

Rare gene variants may multiply Alzheimer's disease risk

Alzheimer's disease is the most common form of dementia worldwide, and its development is influenced by a combination of genetic and environmental factors. In recent years, the PLCG2 gene and its encoded enzyme, PLCγ2, have ...

Video games built for prevention can reduce teen depression

Few parents or teachers are likely to suggest that teenagers could benefit from playing more video games. But a new study suggests that a growing class of educational games may be a highly effective tool for treating and ...

ULTRA maps glioma margins in 3D within 30 minutes

One of the major challenges in glioma surgery is that tumor boundaries are often difficult to define. Diffuse gliomas can infiltrate surrounding brain tissue beyond what surgeons can see directly or what conventional imaging ...

Overlooked plant proteins may boost gut health

Plant-based diets are good for you. They promote gut, immune, metabolic and cardiovascular health, in part by cultivating a diverse community of intestinal bacteria. These benefits have long been known to stem partly from ...

Human tissue model tracks glioblastoma invasion cell by cell

Glioblastoma is a malignant brain tumor and is among the most aggressive cancers in humans. Despite multimodal therapy with surgery, radiation and chemotherapy, there is still no cure. A major reason is the tumor's invasive ...

Dreams drain energy: The REM sleep paradox

The brain demands a lot of energy compared with other organs. However, it can also make do when energy supplies are scarce, flexibly processing information using what is available. How the brain resourcefully allocates this ...