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Genetics
Distant relatedness in biobanks harnessed to identify undiagnosed genetic disease
An innovative analysis of shared segments within the genome—an indication of distant "relatedness"—has identified undiagnosed cases of Long QT syndrome, a rare disorder that can lead to abnormal heart rhythms, fainting ...
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Oncology & Cancer
Circadian disruption, gut microbiome changes linked to colorectal cancer progression
Research from the University of California, Irvine has revealed how disruption of the circadian clock, the body's internal, 24-hour biological pacemaker, may accelerate the progression of colorectal cancer by affecting the ...
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Medical research news
Hydrogel with ultrasound activation enables sustained drug release
Researchers at Michigan Medicine have developed a composite hydrogel capable of achieving sustained, steady drug release using ultrasound as a trigger.
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New drug for schizophrenics has experts excited
Experts expressed enthusiasm Friday after US health regulators approved the first new form of treatment for schizophrenia in decades.
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Multiple surgeries could contribute to cognitive decline in older people
Multiple surgeries could lead to cognitive decline, a University of Sydney study has found, using data from the United Kingdom's Biobank to analyze half a million patients aged 40 to 69 and followed over 20 years of brain ...
20 hours ago
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Study finds estrogens play a hidden role in cancers, inhibiting a key immune cell
Estrogens are known to drive tumor growth in breast cancer cells that carry its receptors, but a new study by Duke Cancer Institute researchers unexpectedly finds that estrogens play a role in fueling the growth of breast ...
17 hours ago
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Clinical cancer research in the US is increasingly dominated by pharmaceutical industry sponsors, study finds
Researchers at Fred Hutch Cancer Center identified a substantial increase over the past decade in the proportion of patients with cancer in the U.S. who participate in pharmaceutical industry sponsored clinical trials compared ...
17 hours ago
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Two studies find SARS-CoV-2 virus becoming resistant to antiviral drugs used to treat patients
Two studies have found that the virus that causes COVID-19 is becoming resistant to two drugs used to treat patients with infections.
Automatic speech recognition learns to understand people with Parkinson's disease—by listening to them
As Mark Hasegawa-Johnson combed through data from his latest project, he was pleasantly surprised to uncover a recipe for Eggs Florentine. Sifting through hundreds of hours of recorded speech will unearth a treasure or two, ...
18 hours ago
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A chain of intergenerational violence: Study finds link between adverse childhood experiences and elder abuse
New research shows the connection between adverse childhood experiences (ACEs), such as physical or emotional abuse, and an increased risk of people growing up to be abusive against older generations. While generational trauma ...
19 hours ago
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Researchers discover what hinders DNA repair in patients with Huntington disease
Researchers with McMaster University have discovered that the protein mutated in patients with Huntington disease doesn't repair DNA as intended, impacting the ability of brain cells to heal themselves.
17 hours ago
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Commonly used drug could transform treatment of rare muscle disorder
Lamotrigine, a drug commonly used to treat epilepsy and certain mood disorders, has been shown to be an excellent treatment option for a rare genetic neuromuscular disease known as non-dystrophic myotonia, in a world-first ...
18 hours ago
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Strategy to combat breast cancer involves two-pronged attack on enzyme that 'feeds' tumor
A study led by Brazilian researchers and reported in an article published in the journal Nature Communications proposes that simultaneously targeting the enzyme glutaminase and the protein HuR, both of which are essential ...
18 hours ago
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Treatments that maintain the health of synapses may help prevent, mitigate the symptoms of prion disease
Genetic prion disease generally manifests with cognitive difficulties, poor muscle control and abrupt jerking movements of muscle groups and/or entire limbs. The three major phenotypes of genetic prion disease are genetic ...
18 hours ago
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Two proteins involved in centrosome function linked to congenital developmental disorders
Centrosomes are small structures in cells with many essential functions, including roles in cell signaling and in organizing a cell's cytoskeleton. Centrosome dysfunction contributes to diseases like cancer and congenital ...
18 hours ago
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Growing up with a dog may be good for your gut health, study finds
Dog lovers can attest to the range of benefits that come with having a canine companion, but improved gut health likely isn't one of them.
21 hours ago
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Fiber photometry technique finds serotonin levels in brain increase with reward value
Serotonin is often referred to as the "happiness molecule." It plays a critical role in affecting mood levels and is also a neurotransmitter that sends signals within the brain and the body.
19 hours ago
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Mouse study explores how nerve cells repair themselves
New mouse model research led by scientists at The Ohio State University Wexner Medical Center, College of Medicine and Imperial College London explored how nerve cells repair themselves, which could lead to new treatments ...
21 hours ago
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How changes in risk factors may be contributing to growing number of babies born prematurely
Preterm births have increased by more than 10% over the past decade, with racial and socioeconomic disparities persisting over time, according to a new study analyzing more than five million births.
20 hours ago
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Research reveals mechanism of effector-triggered immunity
A pair of studies examining immune response in C. elegans reveal broad implications for understanding pathogen detection in higher animals and the evolutionary origins of immunity itself.
20 hours ago
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