Page 5 - American Society for Biochemistry and Molecular Biology

Medical research

Sandhoff disease study shows proof of principle for gene therapy

Babies with the rare, deadly genetic disorder Sandhoff disease begin to miss developmental milestones just months after birth. Lacking muscle tone, they never learn to sit up, develop heads too large to lift and eventually ...

Oncology & Cancer

The sugar-attaching enzyme that defines colon cancer

Researchers have identified an enzyme that is absent in healthy colon tissue but abundant in colon cancer cells, according to a report in the Jan. 26 issue of the Journal of Biological Chemistry. The enzyme appears to drive ...

Parkinson's & Movement disorders

Tracing the path of Parkinson's disease proteins

As neurodegenerative disorders such as Parkinson's and Alzheimer's disease progress, misfolded proteins clump together in neurons, recruiting normal proteins in the cell to also misfold and aggregate. Cells in which this ...

Obstetrics & gynaecology

Study yields potential drug targets for preeclampsia patients

Preeclampsia, the most common complication of pregnancy, is a major cause of premature delivery and both maternal and fetal death, yet what causes the syndrome remains unclear. A new study indicates that molecules that send ...

HIV & AIDS

Coral reefs provide potent new anti-HIV proteins

Researchers have discovered a new class of proteins capable of blocking the HIV virus from penetrating T-cells, raising hope that the proteins could be adapted for use in gels or sexual lubricants to provide a potent barrier ...

Medical research

Insights into a new therapy for a rare form of cystic fibrosis

Scientists at the Hospital for Sick Children in Toronto have established that a drug recently approved by the U.S. Food and Drug Administration to treat a rare form of cystic fibrosis works in an unconventional way. Their ...

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