Sanford-Burnham Medical Research Institute

The Sanford-Burnham Medical Research Institute, previously Burnham Institute for Medical Research, is a non-profit medical research institute with locations in La Jolla, California, Orlando, Florida, and Santa Barbara, California. The more than 850 scientists at Sanford-Burnham are focused on revealing the fundamental molecular causes of various diseases, with research including topics such as cancer, neuroscience, stem cell research, diabetes and obesity. Research at Sanford-Burnham is supported by funding from National Institutes of Health, National Cancer Institute, and Juvenile Diabetes Research Foundation among others, and partnerships with pharmaceutical companies such as Johnson & Johnson Pharmaceutical Research and Development. In 2008, Sanford-Burnham was awarded a $97.9 million grant by NIH to establish a high-throughput screening screening center. William H. Fishman, M.D., Ph.D., and his wife Lillian Fishman founded the La Jolla Cancer Research Foundation in 1976 after retiring from Tufts University School of Medicine. The Foundation focused on oncodevelopment, the study of developmental biology in conjunction with oncology as a means to better understand cancer.

Website
http://www.sanfordburnham.org
Wikipedia
http://en.wikipedia.org/wiki/Sanford-Burnham_Medical_Research_Institute

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Alzheimer's disease & dementia

New drug reverses loss of brain connections in Alzheimer's disease

The first experimental drug to boost brain synapses lost in Alzheimer's disease has been developed by researchers at Sanford-Burnham Medical Research Institute. The drug, called NitroMemantine, combines two FDA-approved medicines ...

Medical research

Using stem cells to grow new hair

In a new study from Sanford-Burnham Medical Research Institute (Sanford-Burnham), researchers have used human pluripotent stem cells to generate new hair. The study represents the first step toward the development of a cell-based ...

Medical research

How belly fat differs from thigh fat—and why it matters

Men tend to store fat in the abdominal area, but don't usually have much in the way of hips or thighs. Women, on the other hand, are more often pear-shaped—storing more fat on their hips and thighs than in the belly. Why ...

Genetics

'Junk DNA' drives embryonic development

An embryo is an amazing thing. From just one initial cell, an entire living, breathing body emerges, full of working cells and organs. It comes as no surprise that embryonic development is a very carefully orchestrated process—everything ...

Alzheimer's disease & dementia

Brain enzyme is double whammy for Alzheimer's disease

The underlying causes of Alzheimer's disease are not fully understood, but a good deal of evidence points to the accumulation of β-amyloid, a protein that's toxic to nerve cells. β-amyloid is formed by the activity ...

Oncology & Cancer

Scientists solve structure of important protein for tumor growth

In a collaborative study between Sanford Burnham Prebys Medical Discovery Institute (SBP) and the Argonne National Laboratory, scientists have used a highly specialized X-ray crystallography technique to solve the protein ...

Medical research

Researchers unravel molecular roots of Down syndrome

Sanford-Burnham researchers discover that the extra chromosome inherited in Down syndrome impairs learning and memory because it leads to low levels of SNX27 protein in the brain.

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