Last update:
Medical research news
Medical research
Loss of salt and body fluid stimulates kidney regeneration in mice
A loss of salt and body fluid can stimulate kidney regeneration and repair in mice, according to a new study led by USC Stem Cell scientist Janos Peti-Peterdi and published in the Journal of Clinical Investigation.
14 hours ago
0
26
Medical research
Chemical conjugation mitigates immunotoxicity of chemotherapy of lipid nanoparticles
While chemotherapy can stimulate antitumor immunity, it may also impair immune cell function and induce lymphodepletion, reducing the effectiveness of subsequent immunotherapy. Thus, nanoparticle-based drug delivery systems ...
17 hours ago
0
46
New study sheds light on potassium channels to help researchers design better drugs
Potassium channels are openings that allow charged potassium atoms to cross the cell membrane. Voltage-gated potassium channels—which open only when a specific voltage is reached across the cell membrane—are essential ...
Jun 27, 2024
0
52
Lactate shuttle in skeletal muscle impacts myofiber types and exercise activity
A research team led by Prof. Chen Yan and Prof. Yang Lifeng from the Shanghai Institute of Nutrition and Health of the Chinese Academy of Sciences revealed a physiological function of monocarboxylate transporter 1 (MCT1) ...
Jun 27, 2024
0
30
Further transparency needed in cancer clinical trials
Despite significant improvements in data sharing for cancer clinical trials over the last 10 years, further changes are still needed to ensure patient-centered care, medical advancements, and trust in the pharmaceutical industry, ...
Jun 27, 2024
0
0
Patients receiving exceptions to participate in targeted therapy trial have similar outcomes to eligible participants
Eligibility requirements for clinical trials help protect patients whose comorbidities may put them at an additional risk of severe harm from the treatment being tested. Further, they help ensure that analyses are performed ...
Jun 27, 2024
0
0
Large analysis finds that for healthy adults, taking multivitamins daily is not associated with a lower risk of death
A large analysis of data from nearly 400,000 healthy U.S. adults followed for more than 20 years has found no association between regular multivitamin use and lower risk of death. The study, "Multivitamin Use and Mortality ...
Jun 26, 2024
3
359
Research uncovers 'molecular glue' that helps ensure memory formation and stabilization
Whether it's a first-time visit to a zoo or when we learned to ride a bicycle, we have memories from our childhoods kept well into adult years. But what explains how these memories last nearly an entire lifetime?
Jun 26, 2024
0
55
University of Minnesota retracts pioneering studies in stem cells, Alzheimer's disease
Years after questions were raised about their integrity, two of the University of Minnesota's highest-profile scientific discoveries have been retracted in one week—one that offered hope over the therapeutic potential of ...
Jun 26, 2024
0
24
Electroconvulsive therapy or ketamine? Clinical factors affect outcomes
Patients with moderate to severe treatment-resistant depression (TRD) might have better symptom relief from ketamine infusions than from electroconvulsive therapy (ECT), but those with severe TRD could benefit more from ECT ...
Jun 26, 2024
0
24
A new method to study immune cells offers hope for finding new disease treatments
Macrophages play a critical role in the immune system by fighting infections and aiding in tissue repair. Understanding how these cells are activated in different scenarios is important for developing new medical treatments. ...
Jun 26, 2024
0
9
Review highlights advances and future needs in AL amyloidosis treatment
AL (immunoglobulin light chain) amyloidosis is a rare disease that often results in progressive organ dysfunction, organ failure and eventual death.
Jun 26, 2024
0
0
The largest repository of transcription factor binding data in human tissues compiled to date
Transcription factors (TFs) are proteins that bind to specific DNA sequences, regulating the transcription of genetic information from DNA to messenger RNA (mRNA). These proteins play a pivotal role in the regulation of gene ...
Exploring the antidepressant effects of oleacein, a rare compound found in olives
Researchers are exploring natural compounds as potential alternatives to conventional antidepressants, which often yield inconsistent results. Compounds that activate the TrkB receptor are of particular interest, as this ...
Jun 25, 2024
0
2
Researchers uncover the cellular secrets of healthy tendons
Research has unveiled the intricate cellular landscape of healthy human hamstring tendons, shedding new light on this vital yet often overlooked component of our musculoskeletal system.
Jun 24, 2024
0
14
C. elegans study finds mRNA balance in cells influences lifespan
Why do some people live for longer than others? The genes in our DNA sequence are important, helping avoid disease or maintain general health, but differences in our genome sequence alone explain less than 30% of the natural ...
Jun 21, 2024
0
90
Study reveals evolution of human cold and menthol sensing protein, offers hope for future non-addictive pain therapies
Chronic pain affects millions worldwide, and current treatments often rely on opioids, which carry risks of addiction and overdose. Non-addictive alternatives could revolutionize pain management, and new research targeting ...
Jun 21, 2024
0
57
Researchers develop new compound designed to treat drug-resistant acute myeloid leukemia
Researchers at Purdue University's College of Science have developed a patent-pending compound called HSN748 to treat drug-resistant acute myeloid leukemia (AML). AML is a cancer that begins in bone marrow and sometimes metastasizes ...
Jun 21, 2024
0
6
Scientists generate kidney organoids with a complex vascular system
A study led by the Institute for Bioengineering of Catalonia (IBEC) describes a new approach to producing mini-kidneys in the laboratory that mimic a complex vasculature, similar in some characteristics to those of the human ...
Jun 21, 2024
0
14
Expert suggests key target for rejuvenation treatments needs 're-brand'
The quest for rejuvenation treatments often targets senescent cells, despite them having a positive physiological role in health in many recent cases, a leading researcher has warned.
Jun 21, 2024
0
0
