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Silicon exoskeletons for blood cells: Engineered blood cells successfully transfused between species

A study by an international research collaborative reports a stunning blood modification method that not only protects red blood cells for perfusion-based transplant organ cryostorage, but could make blood types cross-compatible ...

Medical research

Scientists discover a new cardiovascular risk factor and identify a drug able to reduce its effects

To the known risk factors for cardiovascular disease—high blood pressure, high cholesterol, diabetes, overweight and obesity, smoking, and physical inactivity—a new one has to be added, clonal hematopoiesis. This condition ...

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Ultrasound device shows promise for treating chronic pain

Pain is a necessary biological signal, but a variety of conditions can cause those signals to go awry. For people with chronic pain, the root is often faulty signals emerging deep within the brain, giving false alarms about ...

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Review highlights advances in kidney cancer research and care

New insights into the biology of kidney cancer, including those informed by scientific discoveries that earned a Nobel Prize, have led to advances in treatment and increased survival rates, according to a review by UNC Lineberger ...

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Key discovery advances fight to reduce breast cancer recurrence

In looking for new ways to fight breast cancer, scientists from Duke-NUS Medical School have unmasked a surprising role of a protein generally associated with cancer growth. They have discovered that in estrogen receptor-positive ...

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Study of pythons could lead to new therapies for heart disease

In the first 24 hours after a python devours its massive prey, its heart grows 25%, its cardiac tissue softens dramatically, and the organ squeezes harder and harder to more than double its pulse. Meanwhile, a vast collection ...

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Intervening to stop bone loss

Bone remodeling in the body involves a balancing act between osteoblasts, cells that build bone, and osteoclasts, cells that break it down. Diseases such as osteoporosis, arthritis, and periodontitis involve bone loss, and ...

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Mode-of-action of T-cell immunotherapies in focus

A new 3D imaging technique brings the working mode of T-cell immunotherapies into live view. T-cell immunotherapy is already leading to promising results in some children with leukemia. Researchers plan to use the new imaging ...

Medical research

Scientists discover clue to stopping Lassa virus infection

Lassa fever is a viral illness that is far too common in West Africa. Although it can have a mortality rate of 15% in severe cases, up to 90% in pregnant women, and causes deafness in a quarter of survivors, there is no vaccine ...

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Anti-amyloid drugs and Alzheimer's disease

An estimated 50 million people around the world have Alzheimer's disease (AD), and perhaps twice that number are unknowingly "incubating" the disease during its long presymptomatic period. The total cost of caring for AD ...

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Institute working to accelerate COVID-19 drug development

As part of ongoing efforts to make a live attenuated vaccine for COVID-19, Texas Biomedical Research Institute Professor Luis Martinez-Sobrido and his team developed a weakened, or attenuated, version of SARS-CoV-2 that does ...

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Why immunology research needs a more human focus

Vaccinology—once a hit-and-miss matter of injecting a killed or severely weakened pathogen into a patient's arm and hoping for the best—has undergone major advances with the advent of analytical technologies that permit ...

Medical research

Brain stimulation improves motor skill learning at older age

Even though we don't think about it, every movement we make in our daily life essentially consists of a sequence of smaller actions in a specific order. The only time we realize this is when we have to learn a new motor skill, ...