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Silicon exoskeletons for blood cells: Engineered blood cells successfully transfused between species

A study by an international research collaborative reports a stunning blood modification method that not only protects red blood cells for perfusion-based transplant organ cryostorage, but could make blood types cross-compatible ...

Medical research

Scientists discover a new cardiovascular risk factor and identify a drug able to reduce its effects

To the known risk factors for cardiovascular disease—high blood pressure, high cholesterol, diabetes, overweight and obesity, smoking, and physical inactivity—a new one has to be added, clonal hematopoiesis. This condition ...

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Ultrasound device shows promise for treating chronic pain

Pain is a necessary biological signal, but a variety of conditions can cause those signals to go awry. For people with chronic pain, the root is often faulty signals emerging deep within the brain, giving false alarms about ...

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Review highlights advances in kidney cancer research and care

New insights into the biology of kidney cancer, including those informed by scientific discoveries that earned a Nobel Prize, have led to advances in treatment and increased survival rates, according to a review by UNC Lineberger ...

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Key discovery advances fight to reduce breast cancer recurrence

In looking for new ways to fight breast cancer, scientists from Duke-NUS Medical School have unmasked a surprising role of a protein generally associated with cancer growth. They have discovered that in estrogen receptor-positive ...

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Study of pythons could lead to new therapies for heart disease

In the first 24 hours after a python devours its massive prey, its heart grows 25%, its cardiac tissue softens dramatically, and the organ squeezes harder and harder to more than double its pulse. Meanwhile, a vast collection ...

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Protein discovery reinvigorates promising new therapeutic

Several years ago, a promising therapeutic using stem cell factor (SCF) emerged that could potentially treat a variety of ailments, such as ischemia, heart attack, stroke and radiation exposure. However, during clinical trials, ...

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UHRF1 suppresses pathogeneses in rheumatoid arthritis

Rheumatoid arthritis (RA) is characterized by chronic inflammation of synovium, eventually leading to joint destruction. Epigenetic alteration (the mechanism of gene expression regulation without DNA sequence changes), such ...

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Lessons on how to sleep: What we can learn from worms

Sleep regulation in worms is not as different from sleep regulation in mammals, including humans, as you may think. Therefore, knowing how worms switch between being asleep and being awake can tell us a lot of useful information ...

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Chronic lung disease treatment hits speed bump

A promising avenue of research into chronic lung disease treatment has hit a speed bump, with a new study showing that 3D manufacturing mesenchymal stem cells (MSCs) may not be the panacea hoped for by researchers.

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Exploring a novel treatment for K-Ras mutant pancreatic tumors

Often undetected until it has progressed to an advanced stage, pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer. The K-Ras mutant pancreatic cancer is one of the most common types. At present, there are no effective ...

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Fecal transplant throws new light on inflammatory bowel disease

Inflammatory bowel disease is accompanied by a number of changes in the intestines, such as a change in epithelial permeability, a change in the composition of the microorganisms, and altered levels of antimicrobial substances ...

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Scientists discover new clues to liver cancer progression

A team of researchers from the College of Design and Engineering, the N.1 Institute for Health and the Cancer Science Institute of Singapore at the National University of Singapore has recently engineered in vitro tumor models ...

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Cellular secrets of ageing unlocked by researchers

New research has uncovered how genetic changes that accumulate slowly in blood stem cells throughout life are likely to be responsible for the dramatic change in blood production after the age of 70.