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Investigational mpox mRNA vaccine more effectively reduces disease severity in primates compared to available vaccines

The most frequently used mpox vaccine provides partial immunity to the disease but isn't always able to prevent severe symptoms or disease transmission. A new vaccine candidate from Moderna, mRNA-1769, more effectively limits ...

Medical research

Newly discovered gene may influence longevity in humans

Sleep, fasting, exercise, green porridge, black coffee, a healthy social life—there is an abundance of advice out there on how to live a good, long life. Researchers are working hard to determine why some people live longer ...

Medical research

New approach moves cell therapy closer to treating many disorders

A new approach to manufacturing cells that secrete and deliver therapies to specific parts of the body has taken a big step toward one day repairing joints and damage after heart attacks, countering transplant rejection and ...

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Blood stem cell research could transform bone marrow transplants

Melbourne researchers have made a world first breakthrough in creating blood stem cells that closely resemble those in the human body. And the discovery could soon lead to personalized treatments for children with leukemia ...

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Ultrasound device shows promise for treating chronic pain

Pain is a necessary biological signal, but a variety of conditions can cause those signals to go awry. For people with chronic pain, the root is often faulty signals emerging deep within the brain, giving false alarms about ...

Medical research

Review highlights advances in kidney cancer research and care

New insights into the biology of kidney cancer, including those informed by scientific discoveries that earned a Nobel Prize, have led to advances in treatment and increased survival rates, according to a review by UNC Lineberger ...

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Barriers migrants face accessing healthcare during the pandemic

Doctors of the World (DOTW), the Nuffield Foundation and the University of Birmingham have today published "Migration and Vulnerability During the Pandemic: Barriers to Wellbeing," which has revealed that refugees, asylum ...

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A specific subset of immune cells that mitigates kidney damage

The immune system is highly complex. For example, a particular class of cells called mononuclear phagocytes (MNPs) plays important roles in the uptake and disposal of damaged cells, the elimination of invasive pathogens and ...

Medical research

A new injectable hydrogel for cartilage repair

A team of researchers affiliated with a host of institutions in China has developed an injectable hydrogel for use in repairing damaged cartilage. In their paper published in the journal Science Advances, the group describes ...

Medical research

A fountain of youth for ageing stem cells in bone marrow

As we age, our bones become thinner, we suffer fractures more often, and bone-diseases such as osteoporosis are more likely to occur. One responsible mechanism involves the impaired function of the bone-marrow stem cells, ...

Medical research

Experiments challenge cognitive-map hypothesis in mice

A team of researchers at the Wellcome Centre for Neural Circuits and Behaviour, in the U.K. reports a study that challenges the cognitive-map hypothesis for animals. In their paper published in the journal Nature Neuroscience, ...

Medical research

Curbing short pregnancy gaps in Africa

Chichi Okafor, a 30-year-old Nigerian woman, unexpectedly became pregnant again before her daughter turned six months old.

Medical research

Development study reveals origins of inflammatory bowel disease

Many diseases have their origin in early human development, and today (8 September), two publications in Nature reveal how researchers from the Human Cell Atlas (HCA) consortium are advancing understanding of this. The global ...

Medical research

Researchers make glycomics data AI-ready

Researchers at the University of California San Diego have created a tool that allows glycomics datasets to be analyzed using explainable Artificial Intelligence (AI) systems and other machine learning approaches. In a recent ...