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World Trade Center exposure linked to increased DNA methylation

World Trade Center (WTC) exposure is associated with increased DNA methylation, which may contribute to breast cancer, according to a study published in the June issue of Environmental Epidemiology.

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Air pollution and mortality: Global study reveals persistent health risks despite declining pollutant levels

Even when air pollutant concentrations decrease, the health risks posed by these pollutants can remain consistently high. This is the conclusion of an international study conducted under the leadership of researchers from ...

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Newly discovered gene may influence longevity in humans

Sleep, fasting, exercise, green porridge, black coffee, a healthy social life—there is an abundance of advice out there on how to live a good, long life. Researchers are working hard to determine why some people live longer ...

Medical research

New approach moves cell therapy closer to treating many disorders

A new approach to manufacturing cells that secrete and deliver therapies to specific parts of the body has taken a big step toward one day repairing joints and damage after heart attacks, countering transplant rejection and ...

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Blood stem cell research could transform bone marrow transplants

Melbourne researchers have made a world first breakthrough in creating blood stem cells that closely resemble those in the human body. And the discovery could soon lead to personalized treatments for children with leukemia ...

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Ultrasound device shows promise for treating chronic pain

Pain is a necessary biological signal, but a variety of conditions can cause those signals to go awry. For people with chronic pain, the root is often faulty signals emerging deep within the brain, giving false alarms about ...

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'Good cholesterol' may protect liver

The body's so-called good cholesterol may be even better than we realize. New research from Washington University School of Medicine in St. Louis suggests that one type of high-density lipoprotein (HDL) has a previously unknown ...

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New platform could enable personalized immunotherapy

An innovative testing platform that more closely mimics what cancer encounters in the body may allow for more precise, personalized therapies by enabling the rapid study of multiple therapeutic combinations against tumor ...

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AI's human protein database a 'great leap' for research

Scientists on Thursday unveiled the most exhaustive database yet of the proteins that form the building blocks of life, in a breakthrough observers said would "fundamentally change biological research".

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Should changes made to clinical trials during pandemic be kept?

(HealthDay)—Many of the alterations made to clinical trial procedures during the COVID-19 pandemic should be implemented in the post-COVID-19 roadmap, according to an article published online July 21 in Cancer Discovery.

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New approach eradicates breast cancer in mice

A new approach to treating breast cancer kills 95-100% of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases in bone, brain, liver and lungs. The newly developed drug, called ...

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Study finds calcium precisely directs blood flow in the brain

Unlike the rest of the body, there is not enough real estate in the brain for stored energy. Instead, the brain relies on the hundreds of miles of blood vessels within it to supply fresh energy via the blood. Yet, how the ...

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Take two: Integrating neuronal perspectives for richer results

Every brain function, from standing up to deciding what to have for dinner, involves neurons interacting. Studies focused on neuronal interactions extend across domains in neuroscience, primarily using the approaches of spike ...

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A novel method for the rapid repair of peripheral nerve injuries

Each year, hundreds of thousands of people worldwide suffer from peripheral nerve injuries, which often leave them with long-term disabilities. The peripheral nervous system is analogous to the circulatory system; a network ...

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Novel treatments to prevent infections in patients with leukemia

Using either universal myeloid progenitor cells or expanded umbilical cord blood transplantation could help prevent infections in patients with leukemia, according to a pair of studies co-authored by Olga Frankfurt, MD, associate ...

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Predicting if COVID-19 clinical trials will fail or succeed

In order to win the battle against COVID-19, studies to develop vaccines, drugs, devices and re-purposed drugs are urgently needed. Randomized clinical trials are used to provide evidence of safety and efficacy as well as ...

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Gene expression mechanism may have immunity, cancer implications

Alternative polyadenylation (APA) is an RNA processing mechanism that regulates gene expression by generating different ends on RNA transcripts of the same gene. Though it affects more than half of human genes, the significance ...

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New high-tech portal launched to speed hearing loss innovations

Researchers at the University of Maryland School of Medicine (UMSOM) launched a new online tool that could more quickly advance medical discoveries to reverse progressive hearing loss. The tool enables easy access to genetic ...