Research shows interferon-beta regulates excessive alternative splicing in multiple sclerosis
A new study found extensive alternative splicing of messenger RNA in the blood cells of untreated multiple sclerosis patients compared to healthy controls. The study, which showed that highly dysregulated alternative splicing ...
15 hours ago
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Small molecule shows early-stage promise for repairing myelin sheath damage
When treated with a novel protein function inhibitor called ESI1, mice that mimic the symptoms of multiple sclerosis (MS) and lab-prepared human brain cells both demonstrated the ability to regenerate vital myelin coatings ...
May 2, 2024
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A link between breast changes and … UTIs? Mouse study finds these infections provoke a bodily response
Women's health is often talked about in terms of major, life-altering events like pregnancy and menopause. A new study from Cold Spring Harbor Laboratory (CSHL) underscores the importance of considering everyday occurrences' ...
May 2, 2024
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Trial finds increasing or altering smoking-cessation treatment helps persistent smokers quit
For most smokers, quitting on the first attempt is likely to be unsuccessful, but a new study from The University of Texas MD Anderson Cancer Center found patients were more likely to quit if their cessation regimen was altered ...
May 2, 2024
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Study elucidates how energy metabolism is regulated at cellular level
An article published in The FASEB Journal describes a Brazilian study analyzing the correlation between two key energy metabolism regulation processes: the absorption and release of calcium ions by mitochondria, the organelles ...
May 2, 2024
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New study supports psilocybin's potential as an antidepressant
Psilocybin—the active ingredient in "magic" mushrooms—is a more effective treatment for symptoms of depression than controls, providing further support for its potential as an antidepressant, suggests a study published ...
May 1, 2024
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Research on how dietary choline travels through the blood-brain barrier reveals pathway for treating brain disorders
A University of Queensland researcher has found molecular doorways that could be used to help deliver drugs into the brain to treat neurological disorders.
May 1, 2024
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Study finds little gender difference in the perception of ambient room temperature
A large team of medical researchers at the U.S. National Institutes of Health, has found very slight gender differences in temperature perception of a room at ambient conditions and very few gender differences in physiological ...
Father's gut microbes affect the next generation in mouse study
A study from the Hackett group at the European Molecular Biology Laboratory (EMBL) in Rome shows that disrupting the gut microbiome of male mice increases the risk of disease in their future offspring.
May 1, 2024
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An electrifying discovery may help doctors deliver more effective gene therapies
In an effort to improve delivery of costly medical treatments, a team of researchers in electrical engineering at the University of Wisconsin–Madison has developed a stimulating method that could make the human body more ...
Apr 30, 2024
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Cranberry extracts could boost microbiota and counter cardiometabolic diseases
Cranberry extracts appear to improve intestinal microbiota and help prevent chronic diseases such as diabetes and cardiovascular diseases. A recent study by Université Laval and the Institute of Nutrition and Functional ...
Apr 30, 2024
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X-chromosome inactivation may reduce autism risk, study in mice suggests
A study in mice suggests how chromosome inactivation may protect girls from a type of autism disorder inherited from their father's X chromosome.
Apr 30, 2024
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Tsetse fly protein provides anticoagulant with its own on-off switch
Researchers at the University of Sydney and University of Geneva have developed a new anticoagulant, whose anticlotting action can be rapidly stopped "on demand." The result could lead to new surgical and post-operative drugs ...
Apr 30, 2024
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Survival gains seen with assignment to experimental group in cancer trials
For patients with solid tumors, assignment to an experimental group in trials of investigational drugs yields significant survival gains, according to a review published online April 30 in the Annuals of Internal Medicine.
Apr 30, 2024
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Undergraduate student links worm behavior to brain disease
As an undergraduate student in The University of Texas at Arlington's Honors College, Hannah Selvarathinam knew she wanted to conduct research. Near the end of her first year at UTA, the Keller native reached out to the lab ...
Apr 30, 2024
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Scientists discover key bacterium that maintains protective intestinal mucus barrier under low-fiber diet
A low-fiber "Western diet" causes damage to the protective mucus barrier in the gut, and such damage can increase the risk of inflammation and infection. By studying the gut bacteria of people who increased their intake of ...
Apr 29, 2024
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Researchers discover enzymes that open new path to universal donor blood
The quest to develop universal donor blood has taken a decisive step forward. Researchers at DTU and Lund University have discovered enzymes that, when mixed with red blood cells, are able to remove specific sugars that make ...
Apr 29, 2024
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Researchers explore new cell target for cystic fibrosis treatment
A team of University of Saskatchewan (USask) researchers are exploring the role of a newly identified cell type in cystic fibrosis (CF), which could lead to effective new types of treatment.
Apr 29, 2024
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