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Key kidney sensor that helps control fluid balance identified

A new study has identified a critical "pressure sensor" inside the kidney that helps the body control blood pressure and fluid levels. The finding helps explain how the kidneys sense changes in blood volume—something scientists ...

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From lab to clinic: Phase I trial of promising combination therapy for resistant ovarian cancer

Researchers at the University of Colorado Cancer Center have discovered a novel therapy combination that could offer new hope to ovarian cancer patients who do not respond to existing treatments. Conducted entirely at the ...

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Why stress can make your hair fall out: A two-part reaction

It's well known that stress can trigger hair loss. A new paper explores how this happens and how our response to stress can have long-term consequences for our scalps, research that may eventually yield insights into autoimmune ...

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Internet and lack of trust threatens patient–doctor bond

Physicians have worked to earn the trust of their patients for nearly 2,400 years, dating back to the days of Hippocrates, the father of Western medicine. Lucky for Hippocrates that his patients didn't have internet access.

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Stem cell organoids mimic aspects of early limb development

Scientists at EPFL have created a scalable 3D organoid model that captures key features of early limb development, revealing how a specialized signaling center shapes both cell identity and tissue organization.

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The 'Miracle Mineral Solution'—amazing cure or toxic illusion?

Miracle Mineral Solution, also known as MMS, has been marketed for years as a purported miracle cure for various conditions, including cancer, autism, and COVID-19. MMS is the marketing name for sodium chlorite (NaClO₂), ...

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When ribosomes collide, cells launch emergency stress defenses

Ribosomes, the protein factories of the cell, are essential for all living organisms. They bind to mRNA and move along the messenger molecule, reading the genetic code as they go. Using this information, they link amino acids ...

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How statins harm muscles—and how to stop it

Statins have transformed heart health, saving millions of lives by lowering cholesterol and reducing the risk of heart attacks and strokes. But for many patients, these drugs come with a troubling downside: muscle pain, weakness ...

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Advancing patient-reported outcomes in cancer clinical trials

The SISAQOL-IMI consortium, co-led by the European Organization for Research and Treatment of Cancer (EORTC) and Boehringer Ingelheim (BI), has published a paper in The Lancet Oncology outlining how its recommendations for ...

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Microprotein adipogenin found to regulate fat storage in cells

A microprotein called adipogenin appears to play a key role in helping fat cells store lipid droplets—a phenomenon that's pivotal for metabolic health, a study co-led by UT Southwestern Medical Center researchers shows. ...

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New findings on CARD14 protein's role in eczema and psoriasis

Our skin–the body's largest organ–provides the first line of defense against infections and many other threats to our health. Decades of research has shown that a wide range of diseases can occur, or become worse, when ...

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Newly discovered mechanism halts tumor cell replication

A research group at the University of Bologna has identified, for the first time, the specific location and genomic context where DNA breaks occur due to the inhibition of the topoisomerase I, a protein crucial for many biological ...

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New guidelines developed to address racism in bioethics

Columbia University's Division of Ethics Chief Sandra Soo-Jin Lee, Ph.D., is lead author of a new target article in The American Journal of Bioethics, titled "Racial Equity, Diversity and Inclusion in Bioethics: Recommendations ...

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Can targeted therapies be applied to patients with Alzheimer's?

Alzheimer's disease, a debilitating brain disorder with limited treatment options, has long challenged researchers. Specifically, researchers have struggled with slowing the buildup of amyloid beta plaques, harmful clumps ...

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White matter may aid recovery from spinal cord injuries: Study

Injuries, infection and inflammatory diseases that damage the spinal cord can lead to intractable pain and disability. Some degree of recovery may be possible. The question is, how best to stimulate the regrowth and healing ...

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Researchers uncover molecular details of muscle contraction

The connections between the nervous system and muscles develop differently across the kingdom of life. It takes newborn humans roughly a year to develop the proper muscular systems that support the ability to walk, while ...