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Study finds tumor growth fueled by nucleotide salvage

Cancer cells salvage purine nucleotides to fuel tumor growth, including purines in foods we eat, an important discovery with implications for cancer therapies from research by Children's Medical Center Research Institute ...

Medical research

Study highlights association between urinary and vaginal pathogenic E. coli in recurrent cystitis

The human body hosts a diverse array of microorganisms that maintain a delicate balance crucial for overall health. This microbial harmony can be disrupted by factors such as infections, aging, and hormonal changes, leading ...

Medical research

Protein droplets likely don't cause Parkinson's, study suggests

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows a recent study. Rather, the formation of protein into liquid droplets may help to dissolve ...

Medical research

Team develops a sugary-sweet new method for biomarker discovery

Everyone loves a sweet treat, even our cells. While we typically think of sugar as a component of our diet that gives us energy, sugars are also very important in guiding the activity of our cells. Sugar molecules can be ...

Medical research

Researchers identify stem cells in the thymus for the first time

Researchers at the Francis Crick Institute have identified stem cells in the human thymus for the first time. These cells represent a potential new target to understand immune diseases and cancer and how to boost the immune ...

Medical research

Molecule reduces inflammation in Alzheimer's models

Though drug developers have achieved some progress in treating Alzheimer's disease with medicines that reduce amyloid-beta protein, other problems of the disease including inflammation, continue unchecked. In a new study, ...