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Study finds tumor growth fueled by nucleotide salvage

Cancer cells salvage purine nucleotides to fuel tumor growth, including purines in foods we eat, an important discovery with implications for cancer therapies from research by Children's Medical Center Research Institute ...

Medical research

Study highlights association between urinary and vaginal pathogenic E. coli in recurrent cystitis

The human body hosts a diverse array of microorganisms that maintain a delicate balance crucial for overall health. This microbial harmony can be disrupted by factors such as infections, aging, and hormonal changes, leading ...

Medical research

Protein droplets likely don't cause Parkinson's, study suggests

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows a recent study. Rather, the formation of protein into liquid droplets may help to dissolve ...

Medical research

Extending lives of old mice by connecting vessels to young ones

It's more complicated than a fountain of youth, but a team of scientists co-led by Harvard Medical School Professor of Medicine Vadim Gladyshev extended the lives of old mice by connecting their circulatory systems to those ...

Medical research

Researchers find new pathway for HIV invasion of cell nucleus

A study published on August 10, 2023, in the journal Nature Communications has identified a new pathway that human immune deficiency virus (HIV) uses to enter the nucleus of a healthy cell, where it can then replicate and ...

Medical research

A new ally in fighting brain diseases: Your very own skull

Alzheimer's, stroke, multiple sclerosis and other neurological diseases cause severe damage due to neuroinflammation mediated by immune cells. Managing this inflammation poses a significant medical challenge because the brain ...

Medical research

Stem cell therapy rescues symptoms of Alzheimer's disease

In the ongoing search for a cure for Alzheimer's disease, a burgeoning branch of medicine is bringing new hope. Stem cell therapies are already being used to treat various cancers and disorders of the blood and immune system. ...

Medical research

Researchers find a chink in the armor of tuberculosis pathogen

Mycobacterium tuberculosis (Mtb) is the pathogen that causes tuberculosis (TB), the world's deadliest infectious disease. Mtb is so successful and harmful because it can adapt to different conditions inside our bodies, allowing ...