Oncology & Cancer
Boosting sarcoma cell death
Ewing sarcomas – rare, aggressive childhood cancers – are derived from mesenchymal cells in bone and soft tissues, and children with metastatic disease have poor survival.
Oct 5, 2017
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Page 3 - News tagged with adhesive proteins
Neuroscience
Scientists identify important regulator for synapse stability and plasticity
(Medical Xpress)—Using the fruit fly as a model organism, neurobiologists from the Friedrich Miescher Institute for Biomedical Research have identified the L1-type CAM neuroglian as an important regulator for synapse growth, ...
Apr 25, 2013
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Medical research
Protein family linked to autism suppresses the development of inhibitory synapses
Synapse development is promoted by a variety of cell adhesion molecules that connect neurons and organize synaptic proteins. Many of these adhesion molecules are linked to neurodevelopmental disorders; mutations in neuroligin ...
Jan 28, 2013
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Oncology & Cancer
ISG15: A novel therapeutic target to slow breast cancer cell motility
Interferon-stimulated gene 15 (ISG15), a ubiquitin like protein, is highly elevated in a variety of cancers including breast cancer. How the elevated ISG15 pathway contributes to tumorigenic phenotypes remains unclear and ...
Jan 11, 2012
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Oncology & Cancer
Lab-made tissue picks up the slack of Petri dishes in cancer research
New research demonstrates that previous models used to examine cancer may not be complex enough to accurately mimic the true cancer environment. Using oral cancer cells in a three-dimensional model of lab-made tissue that ...
Jan 11, 2012
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Diseases, Conditions, Syndromes
Pill some day may prevent serious foodborne illness, scientist says
Modified probiotics, the beneficial bacteria touted for their role in digestive health, could one day decrease the risk of Listeria infection in people with susceptible immune systems, according to Purdue University research.
Jan 9, 2012
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Oncology & Cancer
Loss of cell adhesion protein drives esophageal and oral cancers in mice
Squamous cell cancers of the oral cavity and esophagus are common throughout the world, with over 650,000 cases of oral cancer each year and esophageal cancer representing the sixth most common cause of cancer death in men. ...
Apr 12, 2011
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Medical research
Cytoskeletal dysregulation underlies Buruli ulcer formation
Mycobacterium ulcerans infects the skin and subcutaneous tissues and secretes a lipid toxin, mycolactone, which causes open skin lesions, known as Buruli ulcers.
Mar 15, 2013
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Immunology
Small peptide ameliorates autoimmune skin blistering disease in mice
Pemphigus vulgaris is a life-threatening autoimmune skin disease that is occurs when the body's immune system generates antibodies that target proteins in the skin known as desomogleins. Desmogleins help to form the adhesive ...
Jan 9, 2013
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