Neuroscience
Dynamic switch for FUS proteinopathy
NUS biologists have discovered that dynamics of the FUS protein plays a key role in FUS proteinopathy that causes certain neurological diseases.
Jul 20, 2017
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Page 7 - News tagged with aggregates
Alzheimer's disease & dementia
Peptide complex in the brain is responsible for Alzheimer's disease
Members of the Faculty of Fundamental Medicine at the Lomonosov Moscow State University have determined the structure of a peptide complex formed in the brain at the early stages of Alzheimer's disease. The research results ...
Jul 17, 2017
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Neuroscience
Study sheds light on link between diseases like Alzheimer's and normal aging in the brain
In a recent Frontiers in Aging Neuroscience paper, Drs. Della David and Frank Baumann together with their teams at the German Center for Neurodegenerative Diseases and Hertie Institute, showed that changes in proteins associated ...
May 17, 2017
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Neuroscience
Scientists add to theory about Huntington's mechanism
Rice University researchers are starting to understand how protein fragments influence the fiber aggregation suspected as a cause of Huntington's disease.
Apr 10, 2017
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Medical research
Research identifies cellular recycling process linked to beneficial effects of enduring mild stress
Biologists have known for decades that enduring a short period of mild stress makes simple organisms and human cells better able to survive additional stress later in life. Now, scientists at Sanford Burnham Prebys Medical ...
Feb 15, 2017
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Medical research
Diagnosing disease before it reveals its presence
A vast class of incurable neurodegenerative disorders are characterized by the aggregation and deposition of aberrant proteins like the amyloid b peptide or a-synuclein, considered to be factors behind the development of ...
Sep 21, 2016
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Alzheimer's disease & dementia
Alzheimer's beginnings prove to be a sticky situation
Laser technology has revealed a common trait of Alzheimer's disease - a sticky situation that could lead to new targets for medicinal treatments.
Sep 12, 2016
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Parkinson's & Movement disorders
Tunneling nanotubes between neurons enable the spread of Parkinson's disease via lysosomes
Scientists from the Institut Pasteur have demonstrated the role of lysosomal vesicles in transporting α-synuclein aggregates, responsible for Parkinson's and other neurodegenerative diseases, between neurons. These proteins ...
Aug 22, 2016
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Genetics
Shedding new light on protein aggregates and the diseases they cause
Researchers from the Massachusetts Institute of Technology and Boston University have developed a system capable of quickly screening millions of yeast cells to measure protein aggregates. Proteins regulate all of the processes ...
Jul 13, 2016
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Alzheimer's disease & dementia
Diagnosing Alzheimer's earlier rather than later
A hallmark of Alzheimer's disease is the appearance of plaques in the brain. The plaques are gradually made up by the aggregation of a small protein called amyloid-beta or "Abeta". Alzheimer's is usually diagnosed late, when ...
May 9, 2016
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